GRK5 Protein Human Active

Description

GRK5 Protein Human Active
Catalog number: B2014105
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 10 μg
Molecular Weight or Concentration: 71.6 kDa
Supplied as: N/A
Applications: molecular tool for various biochemical applications
Storage: -20°C
Keywords: GRK5 Protein
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
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3: Kunapuli P, Onorato JJ, Hosey MM, Benovic JL. Expression, purification, and characterization of the G protein-coupled receptor kinase GRK5 J Biol Chem. 1994 Jan 14;269(2):1099-105.
4: Lee JH, Seo HW, Ryu JY, Lim CJ, Yi KY, Oh KS, Lee BH. KR-39038, a Novel GRK5 Inhibitor, Attenuates Cardiac Hypertrophy and Improves Cardiac Function in Heart Failure Biomol Ther (Seoul). 2020 Sep 1;28(5):482-489.
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6: Zhang Y, Shen GL, Shangguan LJ, Yu Y, He ML. Involvement of NFB signaling in mediating the effects of GRK5 on neural stem cells Brain Res. 2015 May 22;1608:31-9.
7: Yang Y, Wu JJ, Cheng CD, Bao DJ, Dong YF, Li DX, Niu WX, Zhou CX, Niu CS. G-protein-coupled receptor kinase-5 promotes glioblastoma progression by targeting the nuclear factor kappa B pathway Am J Transl Res. 2018 Nov 15;10(11):3370-3384. eCollection 2018.
8: Rowlands RA, Cato MC, Waldschmidt HV, Bouley RA, Chen Q, Avramova L, Larsen SD, Tesmer JJG, White AD. Structure-Based Design of Selective, Covalent G Protein-Coupled Receptor Kinase 5 Inhibitors ACS Med Chem Lett. 2019 Nov 12;10(12):1628-1634.
9: Tran TM, Jorgensen R, Clark RB. Phosphorylation of the beta2-adrenergic receptor in plasma membranes by intrinsic GRK5 Biochemistry. 2007 Dec 18;46(50):14438-49.
10: Adzika GK, Hou H, Adekunle AO, Rizvi R, Adzraku SY, Li K, Deng QM, Mprah R, Ndzie Noah ML, Adu-Amankwaah J, Machuki JO, Shang W, Ma T, Koda S, Ma X, Sun H. Amlexanox and Forskolin Prevents Isoproterenol-Induced Cardiomyopathy by Subduing Cardiomyocyte Hypertrophy and Maladaptive Inflammatory Responses Front Cell Dev Biol. 2021 Sep 24;9:719351.

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