Gly-Pro-pNA (Hydrochloride)

Product Description

Gly-Pro-pNA (Hydrochloride)
Catalog number: B2013109
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 5 mg
Molecular Weight or Concentration: 328.8 g/mol
Supplied as: Lyophilized Powder
Applications: molecular tool for various biochemical applications
Storage: -20°C
Keywords: Gly-Pro p-nitroanilide, GP-pNA
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Kim YB, Kopcho LM, Kirby MS, Hamann LG, Weigelt CA, Metzler WJ, Marcinkeviciene J. Mechanism of Gly-Pro-pNA cleavage catalyzed by dipeptidyl peptidase-IV and its inhibition by saxagliptin (BMS-477118) Arch Biochem Biophys. 2006 Jan 1;445(1):9-18.
2: Divya K, Vivek HK, Priya BS, Nanjunda Swamy S. Rapid detection of DPP-IV activity in porcine serum: A fluorospectrometric assay Anal Biochem. 2020 Mar 1;592:113557.
3: Mäkinen PL, Mäkinen KK, Syed SA. An endo-acting proline-specific oligopeptidase from Treponema denticola ATCC 35405: evidence of hydrolysis of human bioactive peptides Infect Immun. 1994 Nov;62(11):4938-47.
4: Yoshimoto T, Tsuru D. Proline-specific dipeptidyl aminopeptidase from Flavobacterium meningosepticum J Biochem. 1982 Jun;91(6):1899-906.
5: Bauvois B. Murine thymocytes possess specific cell surface-associated exoaminopeptidase activities: preferential expression by immature CD4-CD8- subpopulation Eur J Immunol. 1990 Mar;20(3):459-68.
6: Shibuya-Saruta H, Sugiyama M, Kasahara Y. Colorimetrical rate assay for urinary dipeptidyl peptidase IV (DPPIV) activity using a new substrate J Clin Lab Anal. 1995;9(2):113-8.
7: Nandan AS, Nampoothiri KM. Unveiling aminopeptidase P from Streptomyces lavendulae: molecular cloning, expression and biochemical characterization Enzyme Microb Technol. 2014 Feb 5;55:7-13.
8: Blanco J, Jacotot E, Callebaut C, Krust B, Hovanessian AG. Further characterization of DPP IV-beta, a novel cell surface expressed protein with dipeptidyl peptidase activity Adv Exp Med Biol. 1997;421:193-9.
9: Fu P, Sun W, Lai J, Shen YH, Zhang Z. Identification of two isoforms of Pop in the domestic silkworm, Bombyx mori: Cloning, characterization and expression analysis Gene. 2018 Aug 15;667:101-111.
10: Hinke SA, Kühn-Wache K, Hoffmann T, Pederson RA, McIntosh CH, Demuth HU. Metformin effects on dipeptidylpeptidase IV degradation of glucagon-like peptide-1 Biochem Biophys Res Commun. 2002 Mar 15;291(5):1302-8.

Products Related to Gly-Pro-pNA (Hydrochloride) can be found at Substrates