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EEF1A2 Protein

Original price was: $2,195.00.Current price is: $1,095.00.

Catalog Number: B2016665 (10 µg)
EEF1A2 Protein is a high quality key player in the process of protein synthesis within cells. It helps in the accurate and efficient translation of genetic information from RNA to protein, ensuring that the correct amino acids are brought to the ribosome for building proteins. Additionally, EEF1A2 has been implicated in various cellular functions beyond protein synthesis, such as cytoskeletal organization, cell signaling, and cell proliferation. This product has been used as a molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request.

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Product Description

EEF1A2 Protein
Catalog number: B2016665
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 10 µg
Molecular Weight or Concentration: 54 kDa
Supplied as: Solution
Applications: a molecular tool for various biochemical applications
Storage: -80°C
Keywords: Eukaryotic Translation Elongation Factor 1 Alpha 2
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Qiu FN, Huang Y, Chen DY, Li F, Wu YA, Wu WB, Huang XL. Eukaryotic elongation factor-1α 2 knockdown inhibits hepatocarcinogenesis by suppressing PI3K/Akt/NF-κB signaling World J Gastroenterol. 2016 Apr 28;22(16):4226-37.
2: Jeganathan S, Lee JM. Binding of elongation factor eEF1A2 to phosphatidylinositol 4-kinase beta stimulates lipid kinase activity and phosphatidylinositol 4-phosphate generation J Biol Chem. 2007 Jan 5;282(1):372-80.
3: Migliaccio N, Ruggiero I, Martucci NM, Sanges C, Arbucci S, Tatè R, Rippa E, Arcari P, Lamberti A. New insights on the interaction between the isoforms 1 and 2 of human translation elongation factor 1A Biochimie. 2015 Nov;118:1-7.
4: Vislovukh A, Kratassiouk G, Porto E, Gralievska N, Beldiman C, Pinna G, El’skaya A, Harel-Bellan A, Negrutskii B, Groisman I. Proto-oncogenic isoform A2 of eukaryotic translation elongation factor eEF1 is a target of miR-663 and miR-744 Br J Cancer. 2013 Jun 11;108(11):2304-11.
5: Akintade DD, Chaudhuri B. Identification of proteins involved in transcription/translation (eEF 1A1) as an inhibitor of Bax induced apoptosis Mol Biol Rep. 2020 Sep;47(9):6785-6792.
6: McClatchy DB, Knudsen CR, Clark BF, Kahn RA, Hall RA, Levey AI. Novel interaction between the M4 muscarinic acetylcholine receptor and elongation factor 1A2 J Biol Chem. 2002 Aug 9;277(32):29268-74.
7: Worley MJ Jr, Liu S, Hua Y, Kwok JS, Samuel A, Hou L, Shoni M, Lu S, Sandberg EM, Keryan A, Wu D, Ng SK, Kuo WP, Parra-Herran CE, Tsui SK, Welch W, Crum C, Berkowitz RS, Ng SW. Molecular changes in endometriosis-associated ovarian clear cell carcinoma Eur J Cancer. 2015 Sep;51(13):1831-42.
8: Liu T, Yang Y, Wang D, Xiao Y, Du G, Wu L, Ding M, Li L, Wu C. Human eukaryotic elongation factor 1A forms oligomers through specific cysteine residues Acta Biochim Biophys Sin (Shanghai). 2015 Dec;47(12):1011-7.
9: Bischoff C, Kahns S, Lund A, Jørgensen HF, Praestegaard M, Clark BF, Leffers H. The human elongation factor 1 A-2 gene (EEF1A2): complete sequence and characterization of gene structure and promoter activity Genomics. 2000 Aug 15;68(1):63-70.
10: Panasyuk G, Nemazanyy I, Filonenko V, Negrutskii B, El’skaya AV. A2 isoform of mammalian translation factor eEF1A displays increased tyrosine phosphorylation and ability to interact with different signalling molecules Int J Biochem Cell Biol. 2008;40(1):63-71.

Products Related to EEF1A2 Protein can be found at Proteins

Additional Information

Weight 48 oz
Dimensions 8 × 8 × 8 in

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