D-Galactosamine x HCl
Original price was: $995.00.$495.00Current price is: $495.00.
Catalog Number: B2027240 (1 g)
D-Galactosamine hydrochloride is an amino sugar derivative and key metabolic intermediate derived from galactose. In biochemical, it acts as a selective hepatotoxic agent widely used to induce models of experimental hepatitis, acute liver injury, and RNA synthesis inhibition by depleting intracellular uracil nucleotides. Supplied as a high-purity crystalline solid, this compound serves as a vital reagent for carbohydrate metabolism studies. Custom bulk amounts of this product are available upon request.
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Product Description
D-Galactosamine x HCl
Catalog number: B2027240
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 1 g
Molecular Weight or Concentration: 215.64
Supplied as: Powder
Storage: NA
Keywords: Chondrosamine hydrochloride, 2-Amino-2-deoxy-D-galactopyranose hydrochloride, D-Chondrosamine hydrochloride, 2-Amino-2-deoxy-D-galactose hydrochloride, D-Galactosamine HCl
References:
1. Keppler D, Lesch R, Reutter W, Decker K. Experimental hepatitis in the rat induced by D-galactosamine. Experimental and Molecular Pathology. 1968;9(2):279-290.
2. Decker K, Keppler D. Galactosamine hepatitis: key role of uridine nucleotide deficiency in liver cell injury. Reviews of Physiology, Biochemistry and Pharmacology. 1974;71:77-106.
3. Lesch R, Keppler D, Reutter W, Decker K. The development of galactosamine-induced hepatitis in rats. Virchows Archiv B. 1970;6(1):57-71.
4. Tsutsui H, Matsui K, Okamura H, et al. Pathophysiological roles of interleukin-18 in D-galactosamine-induced acute liver injury in mice. Journal of Hepatology. 2000;32(4):631-639.
5. Galanos C, Freudenberg MA, Reutter W. Galactosamine-induced sensitization to the lethal effects of endotoxin. Proceedings of the National Academy of Sciences. 1979;76(11):5939-5943.
6. Silverstein RM. D-Galactosamine hepatotoxicity and acute liver failure. Hepatology. 1982;2(1):120-125.
7. Al-Saeed FA. Protective effect of quercetin against D-galactosamine-induced hepatotoxicity in rats. Tropical Journal of Pharmaceutical Research. 2014;13(5):721-727.
8. Maes M, Vinken M, Jaeschke H. Experimental models of hepatotoxicity: D-galactosamine-induced liver injury. Archives of Toxicology. 2016;90(7):1545-1552.
9. Shinozuka H, Farber E, Konishi Y, Anukarahanonta T. D-Galactosamine-induced hepatic cell necrosis and altered nucleolar morphology. Federation Proceedings. 1973;32(4):1516-1526.
10. Tiegs G, Wolter M, Wendel A. Tumor necrosis factor is a terminal mediator in galactosamine/endotoxin-induced hepatitis in mice. Biochemical Pharmacology. 1989;38(4):627-631.
D-Galactosamine x HCl
Products Related to D-Galactosamine x HCl can be found at Carbohydrates
Additional Information
| Weight | 0.15 oz |
|---|---|
| Dimensions | 2 × 0.5 × 0.5 in |
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