Sialylglycopeptide (High Purity Peptide)

Description

Sialylglycopeptide (High Purity)
Catalog number: MDP0895
Name: SGP (alpha2,6) Lys-Val-Ala-[O-(5-Acetamido-3,5-dideoxy-D-glycero-alpha-D-galacto-2-nonulopyranosylonic acid)-(2?6)-O-beta-D-galactopyranosyl-(1?4)-O-2-acetamido-2-deoxy-beta-D-glucopyranosyl-(1?2)-O-alpha-D-mannopyranosyl-(1?3)-[O-(5-acetamido-3,5-dideoxy-D-glycero-alpha-D-galacto-2-nonulopyranosylonic acid)-(2?6)-O-beta-D-galactopyranosyl-(1?4)-O-2-acetamido-2-deoxy-beta-D-glucopyranosyl-(1?2)-O-alpha-D-mannopyranosyl-(1?6)]-O-beta-D-mannopyranosyl-(1?4)-O-2-acetamido-2-deoxy-beta-D-glucopyranosyl-(1?4)-N-2-acetamido-2-deoxy-beta-D-glucopyranosyl]-(1?4)-Asn-Lys-Thr
Other name(s): Sialylglycopeptide
Molecular Formula: C₁₁₂H₁₈₉N₁₅O₇₀
Molecular Mass: 2865.8
CAS #: 189035-43-6
Storage Temperature: -20 C

Indication for Use:
This product if for Research Use Only (RUO). This product is not for administration to humans or animals. This product is not for human or veterinary diagnostic or therapeutic use.

Safety:
User must review the Material Safety Data Sheet (MSDS) provided with this product. In addition, this product should not be ingested, inhaled, swallowed or put in contact with eyes, skin or clothes.

References

1: Fukudome H, Yamaguchi T, Higuchi J, Ogawa A, Taguchi Y, Li J, Kabuki T, Ito
K, Sakai F. Large-scale preparation and glycan characterization of
sialylglycopeptide from bovine milk glycomacropeptide and its bifidogenic
properties. J Dairy Sci. 2021 Feb;104(2):1433-1444.

2: Alagesan K, Kolarich D. Improved strategy for large scale isolation of
sialylglycopeptide (SGP) from egg yolk powder. MethodsX. 2019 Apr 9;6:773-778.

3: Liu L, Prudden AR, Bosman GP, Boons GJ. Improved isolation and
characterization procedure of sialylglycopeptide from egg yolk powder. Carbohydr
Res. 2017 Nov 27;452:122-128.

4: Kajihara Y, Yamamoto N, Miyazaki T, Sato H. Synthesis of diverse asparagine
linked oligosaccharides and synthesis of sialylglycopeptide on solid phase. Curr
Med Chem. 2005;12(5):527-50.

5: Sun B, Bao W, Tian X, Li M, Liu H, Dong J, Huang W. A simplified procedure
for gram-scale production of sialylgly_copeptide (SGP) from egg yolks and
subsequent semi-synthesis of Man3GlcNAc oxazoline. Carbohydr Res. 2014 Sep
19;396:62-9.

6: Sugita-Konishi Y, Kobayashi K, Sakanaka S, Juneja LR, Amano F. Preventive
effect of sialylglycopeptide-nondigestive polysaccharide conjugates on
salmonella infection. J Agric Food Chem. 2004 Aug 25;52(17):5443-8.

7: Seko A, Koketsu M, Nishizono M, Enoki Y, Ibrahim HR, Juneja LR, Kim M,
Yamamoto T. Occurence of a sialylgly_copeptide and free sialylglycans in hen’s
egg yolk. Biochim Biophys Acta. 1997 Apr 17;1335(1-2):23-32.

8: Kajihara Y, Yoshihara A, Hirano K, Yamamoto N. Convenient synthesis of a
sialylglycopeptide-thioester having an intact and homogeneous complex-type
disialyl-oligosaccharide. Carbohydr Res. 2006 Jul 24;341(10):1333-40.

9: Okamoto R, Souma S, Kajihara Y. Efficient synthesis of MUC4
sialylglycopeptide through the new sialylation using 5-acetamido-neuraminamide
donors. J Org Chem. 2008 May 2;73(9):3460-6.

10: Parkkinen J, Finne J. Isolation and structural characterization of five
major sialyloligosaccharides and a sialylglycopeptide from normal human urine.
Eur J Biochem. 1983 Nov 2;136(2):355-61.

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