Curcumin/HPGCD Complex
Original price was: $1,795.00.$895.00Current price is: $895.00.
Catalog Number: B2027422 (100 mg)
Curcumin/HPGCD Complex is a specialized host-guest inclusion complex composed of the hydrophobic polyphenol curcumin encapsulated within hydroxypropyl-gamma-cyclodextrin. This supramolecular formulation significantly enhances the aqueous solubility, chemical stability, and bioavailability of curcumin while preserving its antioxidant and anti-inflammatory properties. It serves as a high-performance delivery system tailored for cell culture research applications. Custom bulk amounts of this product are available upon request.
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Product Description
Curcumin/HPGCD Complex
Catalog number: B2027422
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 100 mg
Molecular Weight or Concentration: NA
Supplied as: Chemicals
Storage: RT
Keywords: Curcumin/Hydroxypropyl-beta-cyclodextrin complex, Curcumin/HP-beta-CD complex, Curcumin-HPBCD inclusion complex
References:
1. Yadav, V. R., Suresh, S., Devi, K., & Yadav, S. (2009). Effect of hydroxypropyl-β-cyclodextrin complexation on aqueous solubility, dissolution rate and antifungal activity of curcumin. Carbohydrate Polymers, 75(1), 175-181.
2. Tang, P., Ma, X., Wu, D., Zhang, J., & Xu, J. (2015). Inclusion complex of curcumin with 2-hydroxypropyl-β-cyclodextrin: Preparation, characterization and antioxidant activity. Bioorganic & Medicinal Chemistry Letters, 25(20), 4520-4524.
3. Rachmawati, H., Edityasari, I. N., & Soraya, R. (2013). Formulation and characterization of curcumin–hydroxypropyl-β-cyclodextrin inclusion complex. Journal of Drug Delivery Science and Technology, 23(3), 241-246.
4. Mangolim, C. S., Moriwaki, C., Nogueira, A. C., Sato, F., Baesso, M. L., Neto, A. M., & Matioli, G. (2014). Curcumin–β-cyclodextrin inclusion complex: Stability, solubility, characterization by FT-IR, FT-Raman, X-ray diffraction and photoacoustic spectroscopy, and antioxidant activity. Food Chemistry, 153, 361-370.
5. Mohan, P. R. K., Sankar, G. U., Subrahmanyam, C. V. S., & Suresh, S. (2012). Preparation, characterization and evaluation of curcumin-hydroxypropyl-β-cyclodextrin inclusion complex for anti-inflammatory activity. International Journal of Pharmaceutics, 427(2), 228-234.
6. Yallapu, M. M., Jaggi, M., & Chauhan, S. C. (2010). β-Cyclodextrin-curcumin self-assembly nanoparticles for curcumin delivery in prostate cancer cells. Colloids and Surfaces B: Biointerfaces, 79(1), 113-125.
7. Hegge, A. B., Vance, M. K., & Tønnesen, H. H. (2008). Water-soluble curcumin complexes: Preparation, characterization and stability evaluation. Journal of Pharmaceutical Sciences, 97(7), 2689-2699.
8. Garcea, G., Berry, D. P., Jones, D. J., Singh, R., Dennison, A. R., Farmer, P. B., & Gescher, A. J. (2005). Consumption of the putative chemopreventive agent curcumin by cancer patients: Assessment of curcumin levels in the colorectal tract and cellular effects. Cancer Epidemiology, Biomarkers & Prevention, 14(1), 120-125.
9. Anand, P., Kunnumakkara, A. B., Newman, R. A., & Aggarwal, B. B. (2007). Bioavailability of curcumin: Problems and promises. Molecular Pharmaceutics, 4(6), 807-818.
10. Loftsson, T., & Duchêne, D. (2007). Cyclodextrins and their pharmaceutical applications. International Journal of Pharmaceutics, 329(1-2), 1-11.
Curcumin/HPGCD Complex
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Additional Information
| Weight | 0.15 oz |
|---|---|
| Dimensions | 2 × 0.5 × 0.5 in |
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