BRD8/SMAP2 Antibody Polyclonal

Product Description

BRD8/SMAP2 Antibody Polyclonal
Catalog number: B2016915
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 10 µl
Molecular Weight or Concentration: 145 kDa
Supplied as: Solution
Applications: a molecular tool for various biochemical applications
Storage: -20°C
Keywords: SMAP, p120
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Nishimoto S, Hamajima Y, Toda Y, Toyoda H, Kitamura K, Komurasaki T. Identification of a novel smooth muscle associated protein, smap2, upregulated during neointima formation in a rat carotid endarterectomy model Biochim Biophys Acta. 2002 Jun 7;1576(1-2):225-30.
2: Sun X, Klingbeil O, Lu B, Wu C, Ballon C, Ouyang M, Wu XS, Jin Y, Hwangbo Y, Huang YH, Somerville TDD, Chang K, Park J, Chung T, Lyons SK, Shi J, Vogel H, Schulder M, Vakoc CR, Mills AA. BRD8 maintains glioblastoma by epigenetic reprogramming of the p53 network Nature. 2023 Jan;613(7942):195-202.
3: Yu Z, Chen T, Mo H, Guo C, Liu Q. BRD8, which is negatively regulated by miR-876-3p, promotes the proliferation and apoptosis resistance of hepatocellular carcinoma cells via KAT5 Arch Biochem Biophys. 2020 Oct 30;693:108550.
4: Yamaguchi K, Nakagawa S, Saku A, Isobe Y, Yamaguchi R, Sheridan P, Takane K, Ikenoue T, Zhu C, Miura M, Okawara Y, Nagatoishi S, Kozuka-Hata H, Oyama M, Aikou S, Ahiko Y, Shida D, Tsumoto K, Miyano S, Imoto S, Furukawa Y. Bromodomain protein BRD8 regulates cell cycle progression in colorectal cancer cells through a TIP60-independent regulation of the pre-RC complex iScience. 2023 Apr 1;26(4):106563.
5: Browne JA, NandyMazumdar M, Paranjapye A, Leir SH, Harris A. The Bromodomain Containing 8 (BRD8) transcriptional network in human lung epithelial cells Mol Cell Endocrinol. 2021 Mar 15;524:111169.
6: Wu T, Chen Y, You Q, Jiang Z, Chen X. Targeting bromodomian-containing protein 8 (BRD8): An advanced tool to interrogate BRD8 Eur J Med Chem. 2024 Mar 15;268:116271.
7: Yamada HY, Rao CV. BRD8 is a potential chemosensitizing target for spindle poisons in colorectal cancer therapy Int J Oncol. 2009 Nov;35(5):1101-9.
8: Remillard D, Savage NA, Kedves AT, Paulk J, Chen X, Garcia FJ, Romanowski MJ, Horton PA, Murphy J, Schirle M, Harrington EM, Maxwell MB, Pham HT, Maksimovic I, Thomas JR, Forrester WC. Chemoproteomics Enabled Discovery of Selective Probes for NuA4 Factor BRD8 ACS Chem Biol. 2021 Nov 19;16(11):2185-2192.
9: Lashgari A, Fauteux M, Maréchal A, Gaudreau L. Cellular Depletion of BRD8 Causes p53-Dependent Apoptosis and Induces a DNA Damage Response in Non-Stressed Cells Sci Rep. 2018 Sep 20;8(1):14089.
10: Chen PC, Huang HY, Chung MY, Pan CC. Ossifying low grade endometrial stromal sarcoma with PHF1-BRD8 fusion Cancer Genet. 2021 Aug;256-257:81-85.

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