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Biotinylated SARS-CoV-2 Spike S2 Domain

Original price was: $1,295.00.Current price is: $695.00.

Catalog Number: B2010510 (25 ug)
Biotinylated SARS-CoV-2 Spike S2 Domain is a highly pure biotinylated recombinant SARS-CoV-2 S2 domain from the origical wild type lineage expressed in insect cells. This product has been used as molecular component of many serological and antigenic assays for SARS-CoV-2. It has also been used in a wide array of other biochemical and immunological applications. Custom bulk amounts of this product are available upon request.

Live enquiry about this product via Text/SMS: 1-858-900-3210.

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Product Description

Biotinylated SARS-CoV-2 Spike S2 Domain
Catalog number: B2010510
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 25 ug
Molecular Weight or Concentration: 56 kDa
Supplied as: Lyophilized Powder
Applications: molecular component of many serological and antigenic assays for SARS-CoV-2
Storage: -20℃
Keywords: Spike S2, S2 protein, Biotin S2
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

Download SARS-CoV-2 Brochure

References:
1: Ho M. Perspectives on the development of neutralizing antibodies against
SARS-CoV-2. Antib Ther. 2020 Apr;3(2):109-114.

2: Gobeil SM, Janowska K, McDowell S, Mansouri K, Parks R, Manne K, Stalls V,
Kopp MF, Henderson R, Edwards RJ, Haynes BF, Acharya P. D614G Mutation Alters
SARS-CoV-2 Spike Conformation and Enhances Protease Cleavage at the S1/S2
Junction. Cell Rep. 2021 Jan 12;34(2):108630.

3: Ravichandran S, Coyle EM, Klenow L, Tang J, Grubbs G, Liu S, Wang T, Golding
H, Khurana S. Antibody signature induced by SARS-CoV-2 spike protein immunogens
in rabbits. Sci Transl Med. 2020 Jul 1;12(550):eabc3539.

4: Zheng Z, Monteil VM, Maurer-Stroh S, Yew CW, Leong C, Mohd-Ismail NK,
Cheyyatraivendran Arularasu S, Chow VTK, Lin RTP, Mirazimi A, Hong W, Tan YJ.
Monoclonal antibodies for the S2 subunit of spike of SARS-CoV-1 cross-react with
the newly-emerged SARS-CoV-2. Euro Surveill. 2020 Jul;25(28):2000291.

5: Pace RM, Williams JE, Järvinen KM, Belfort MB, Pace CD, Lackey KA, Gogel AC,
Nguyen-Contant P, Kanagaiah P, Fitzgerald T, Ferri R, Young B, Rosen-Carole C,
Diaz N, Meehan C, Caffe B, Sangster MY, Topham DJ, McGuire MA, Seppo A, McGuire
MK. COVID-19 and human milk: SARS-CoV-2, antibodies, and neutralizing capacity.
medRxiv [Preprint]. 2020 Sep 18:2020.09.16.20196071.

6: Nguyen-Contant P, Embong AK, Kanagaiah P, Chaves FA, Yang H, Branche AR,
Topham DJ, Sangster MY. S Protein-Reactive IgG and Memory B Cell Production
after Human SARS-CoV-2 Infection Includes Broad Reactivity to the S2 Subunit.
mBio. 2020 Sep 25;11(5):e01991-20.

7: Secchi M, Bazzigaluppi E, Brigatti C, Marzinotto I, Tresoldi C, Rovere-
Querini P, Poli A, Castagna A, Scarlatti G, Zangrillo A, Ciceri F, Piemonti L,
Lampasona V. COVID-19 survival associates with the immunoglobulin response to
the SARS-CoV-2 spike receptor binding domain. J Clin Invest. 2020 Dec
1;130(12):6366-6378.

8: Vilcek S. SARS-CoV-2: Zoonotic origin of pandemic coronavirus. Acta Virol.
2020;64(3):281-287.

9: Gobeil S, Janowska K, McDowell S, Mansouri K, Parks R, Manne K, Stalls V,
Kopp M, Henderson R, Edwards RJ, Haynes BF, Acharya P. D614G mutation alters
SARS-CoV-2 spike conformational dynamics and protease cleavage susceptibility at
the S1/S2 junction. bioRxiv [Preprint]. 2020 Oct 12:2020.10.11.335299.
10: Satarker S, Nampoothiri M. Structural Proteins in Severe Acute Respiratory
Syndrome Coronavirus-2. Arch Med Res. 2020 Aug;51(6):482-491.

Products Related to Biotinylated SARS-CoV-2 Spike S2 Domain : SARS-CoV-2

Additional Information

Weight 48 oz
Dimensions 8 × 8 × 8 in

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