Beta Defensin-1 (Human, Recombinant)

Product Description

Beta Defensin-1 (Human, Recombinant)
Catalog number: B2010343
Lot number: Batch Dependent
Expiration Date: Batch dependent
Volume/Weight: 10 ug
pH: 7.4 upon reconstitution
Supplied as: Lyophilized Powder
Appearance: Powder
Applications: highly pure Beta Defensin-1 (Human, Recombinant) expressed in E. coli. This protein acts as an antimicrobial peptide that defends epithelial surfaces including the skin, gastrointestinal, and respiratory tracts.
Storage: -20C
Keywords: rHuBD-1; HBD1; DEFB1
Grade: Biotechnology grade. All components are highly pure (minimum 95%). All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Álvarez ÁH, Martínez Velázquez M, Prado Montes de Oca E. Human β-defensin 1
update: Potential clinical applications of the restless warrior. Int J Biochem
Cell Biol. 2018 Nov;104:133-137.

2: Ryan LK, Diamond G. Modulation of Human β-Defensin-1 Production by Viruses.
Viruses. 2017 Jun 21;9(6):153.

3: Ślebioda Z, Woźniak T, Dorocka-Bobkowska B, Woźniewicz M, Kowalska A. Beta-
defensin 1 gene polymorphisms in the pathologies of the oral cavity-Data from
meta-analysis: Association only with rs1047031 not with rs1800972, rs1799946,
and rs11362. J Oral Pathol Med. 2021 Jan;50(1):22-31.

4: Khayamabed R, Tavalaee M, Taherian SS, Nasr-Esfahani MH. Effect of
recombinant β-defensin 1 protein on human sperm motility and viability.
Andrologia. 2020 Feb;52(1):e13455.

5: Zupin L, Polesello V, Martinelli M, Luppi S, Giolo E, Zito G, Romano F, Segat
L, Crovella S, Ricci G. Human β-defensin 1 in follicular fluid and semen: impact
on fertility. J Assist Reprod Genet. 2019 Apr;36(4):787-797.

6: Kallel A, Ben Salem T, Hammami MB, Said F, Jemaa R, Houman MH, Feki M.
Association of systemic beta-defensin-1 and -20G/A DEFB1 gene polymorphism with
Behçet’s disease. Eur J Intern Med. 2019 Jul;65:58-62.

7: Feng Q, Liu N, Song S, Ma Y. Relationship between β-defensin-1 gene
polymorphism and susceptibility and prognosis of acute respiratory distress
syndrome. Medicine (Baltimore). 2019 Feb;98(5):e14131.
8: Kowalska A, Ślebioda Z, Woźniak T, Zasadziński R, Daszkowska M, Dorocka-
Bobkowska B. Beta-defensin 1 gene polymorphisms at 5′ untranslated region are
not associated with a susceptibility to recurrent aphthous stomatitis. Arch Oral
Biol. 2019 May;101:130-134.

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