Beta-Crosslaps Antibody (Polyclonal)

Product Description

Beta-Crosslaps Antibody
Catalog number: B2010381
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 50 ug
Molecular Weight or Concentration: 150 kDa
Supplied as: Liquid
Appearance: Clear Solution
Applications: a rabbit polyclonal antibody specific to Beta-Crosslaps (bCTx). This antibody has been purified by antigen-specific affinity chromatography, followed by Protein A affinity chromatography.
Storage: -20C
Keywords: Beta-Crosslaps, bCTx, Beta-CTx, Beta CrossLaps
Grade: Biotechnology grade. All solid components are highly pure (minimum 95%). All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Coppolino G, Lucisano G, Rivoli L, Simeoni M, De Paola L, Timpano R, Palmieri
C, Fuiano G. Serum β-crosslaps as predictor of long-term parathyroid hormone
levels in hemodialysis patients. J Investig Med. 2015 Mar;63(3):539-44.

2: Herrmann M, Pape G, Herrmann W. Measurement of serum beta-crosslaps is
influenced by proteolytic conditions. Clin Chem Lab Med. 2002 Aug;40(8):790-4.

3: Vallet S, Hoyle NR, Kyle RA, Podar K, Pecherstorfer M. A role for bone
turnover markers β-CrossLaps (CTX) and amino-terminal propeptide of type I
collagen (PINP) as potential indicators for disease progression from MGUS to
multiple myeloma. Leuk Lymphoma. 2018 Oct;59(10):2431-2438.

4: Okabe R, Nakatsuka K, Inaba M, Miki T, Naka H, Masaki H, Moriguchi A,
Nishizawa Y. Clinical evaluation of the Elecsys beta-CrossLaps serum assay, a
new assay for degradation products of type I collagen C-tlopeptides. Clin Chem.
2001 Aug;47(8):1410-4.

5: Schmidt-Gayk H, Spanuth E, Kötting J, Bartl R, Felsenberg D, Pfeilschifter J,
Raue F, Roth HJ. Performance evaluation of automated assays for beta-CrossLaps,
N-MID-Osteocalcin and intact parathyroid hormone (BIOROSE Multicenter Study).
Clin Chem Lab Med. 2004 Jan;42(1):90-5.

6: Jean G, Lafage-Proust MH, Souberbielle JC, Lechevallier S, Deleaval P,
Lorriaux C, Hurot JM, Mayor B, Mehdi M, Chazot C. Severe secondary
hyperparathyroidism in patients on haemodialysis is associated with a high
initial serum parathyroid hormone and beta-CrossLaps level: Results from an
incident cohort. PLoS One. 2018 Jun 18;13(6):e0199140.
7: Salem AM, Zohny SF, Abd El-Wahab MM, Hamdy R. Predictive value of osteocalcin
and beta-CrossLaps in metastatic breast cancer. Clin Biochem. 2007
Nov;40(16-17):1201-8.

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