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Anti-TCR alpha/beta Antibody Conjugated to PE

Original price was: $1,995.00.Current price is: $995.00.

Catalog Number: B2016793 (50 µg)
Anti-TCR alpha/beta Antibody Conjugated to PE is a high quality antibody that specifically targets the T cell receptor (TCR) alpha/beta complex and is conjugated to a fluorescent dye called phycoerythrin (PE). This conjugated antibody can be used in flow cytometry to detect and analyze T cells expressing the TCR alpha/beta complex. The PE fluorescence allows for the visualization and quantification of these specific T cells in a sample. This product has been used as a molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request.

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Product Description

Anti-TCR alpha/beta Antibody Conjugated to PE
Catalog number: B2016793
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 50 µg
Molecular Weight or Concentration: N/A
Supplied as: Solution
Applications: a molecular tool for various biochemical applications
Storage: 2-8°C
Keywords: Anti-TCR α/β
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Batard P, Szollosi J, Luescher I, Cerottini JC, MacDonald R, Romero P. Use of phycoerythrin and allophycocyanin for fluorescence resonance energy transfer analyzed by flow cytometry: advantages and limitations Cytometry. 2002 Jun 1;48(2):97-105.
2: Holsti MA, McArthur J, Allison JP, Raulet DH. Role of IL-6, IL-1, and CD28 signaling in responses of mouse CD4+ T cells to immobilized anti-TCR monoclonal antibody J Immunol. 1994 Feb 15;152(4):1618-28.
3: Deng R, Khattar M, Xie A, Schroder PM, He X, Chen W, Stepkowski SM. Anti-TCR mAb induces peripheral tolerance to alloantigens and delays islet allograft rejection in autoimmune diabetic NOD mice Transplantation. 2014 Jun 27;97(12):1216-24.
4: Dehghanpisheh K, Marchalonis JJ. Retrovirally induced mouse anti-TCR monoclonals can synergize the in vitro proliferative T cell response to bacterial superantigens Scand J Immunol. 1997 Jun;45(6):645-54.
5: Niederberger N, Buehler LK, Ampudia J, Gascoigne NR. Thymocyte stimulation by anti-TCR-beta, but not by anti-TCR-alpha, leads to induction of developmental transcription program J Leukoc Biol. 2005 May;77(5):830-41.
6: Kim MS, Park D, Lee S, Park S, Kim KE, Kim TS, Park HJ, Cho D. Erythroid Differentiation Regulator 1 Strengthens TCR Signaling by Enhancing PLCγ1 Signal Transduction Pathway Int J Mol Sci. 2022 Jan 13;23(2):844.
7: Noda S, Kosugi A, Saitoh S, Narumiya S, Hamaoka T. Protection from anti-TCR/CD3-induced apoptosis in immature thymocytes by a signal through thymic shared antigen-1/stem cell antigen-2 J Exp Med. 1996 May 1;183(5):2355-60.
8: Vandenbark AA, Hashim GA, Offner H. T cell receptor peptides in treatment of autoimmune disease: rationale and potential J Neurosci Res. 1996 Feb 15;43(4):391-402.
9: Hurst SD, Barrett TA. T-cell responses to enteric antigens Semin Gastrointest Dis. 1996 Jul;7(3):118-23.
10: Wolff CH, Hong SC, von Grafenstein H, Janeway CA Jr. TCR-CD4 and TCR-TCR interactions as distinctive mechanisms for the induction of increased intracellular calcium in T-cell signalling J Immunol. 1993 Aug 1;151(3):1337-45.

Products Related to Anti-TCR alpha/beta Antibody Conjugated to PE can be found at Antiobodies

Additional Information

Weight 48 oz
Dimensions 8 × 8 × 8 in

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