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Anti-Human IgE Antibody Conjugated to Biotin

$695.00

Catalog Number: B2010890 (0.5 mg)
Anti-Human IgE Antibody Conjugated to Biotin is a highly pure biotin-labelled affinity purified polyclonal antibody to human IgE heavy chains. This product has been used as molecular tool for various biochemical studies. It has also been used in a wide array of other biochemical and immunological applications. Custom bulk amounts of this product are available upon request.

Live enquiry about this product via Text/SMS: 1-858-900-3210.

In stock

SKU: B2010890 Categories: ,

Description

Anti-Human IgE Antibody Conjugated to Biotin
Catalog number: B2010890
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 0.5 mg
Molecular Weight or Concentration: na
Supplied as: Solution
Applications: molecular tool for various biochemical studies
Storage: -20°C
Keywords: Biotinylated Anti-Human IgE
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Zghaebi M, Byazrova M, Flicker S, Villazala-Merino S, Campion NJ, Stanek V, Tu A, Breiteneder H, Filatov A, Khaitov M, Niederberger-Leppin V, Eckl-Dorna J, Valenta R. Tracing Human IgE B Cell Antigen Receptor-Bearing Cells With a Monoclonal Anti-Human IgE Antibody That Specifically Recognizes Non-Receptor-Bound IgE Front Immunol. 2021 Dec 20;12:803236.
2: Khodoun MV, Morris SC, Shao WH, Potter C, Angerman E, Kiselev A, Yarawsky AE, Herr AB, Klausz K, Otte A, Peipp M, Finkelman FD. Suppression of IgE-mediated anaphylaxis and food allergy with monovalent anti-FcεRIα mAbs J Allergy Clin Immunol. 2021 May;147(5):1838-1854.e4.
3: Khodoun MV, Morris SC, Angerman E, Potter C, Schuman R, Wunderlich M, Maciag JJ, Sullivan Locker KC, Mulloy JC, Herr AB, Finkelman FD. Rapid desensitization of humanized mice with anti-human FcεRIα monoclonal antibodies J Allergy Clin Immunol. 2020 Mar;145(3):907-921.e3.
4: Weeratna RD, Chikh G, Zhang L, Fraser JD, Thorn JM, Merson JR, McCluskie MJ, Champion BR, Davis HL. Immunogenicity of a peptide-based anti-IgE conjugate vaccine in non-human primates Immun Inflamm Dis. 2016 Apr 1;4(2):135-147.
5: Rabe KF, Watson N, Dent G, Morton BE, Wagner K, Magnussen H, Heusser CH. Inhibition of human airway sensitization by a novel monoclonal anti-IgE antibody, 17-9 Am J Respir Crit Care Med. 1998 May;157(5 Pt 1):1429-35.
6: Kolbinger F, Saldanha J, Hardman N, Bendig MM. Humanization of a mouse anti-human IgE antibody: a potential therapeutic for IgE-mediated allergies Protein Eng. 1993 Nov;6(8):971-80.
7: Laffer S, Hogbom E, Roux KH, Sperr WR, Valent P, Bankl HC, Vangelista L, Kricek F, Kraft D, Grönlund H, Valenta R. A molecular model of type I allergy: identification and characterization of a nonanaphylactic anti-human IgE antibody fragment that blocks the IgE-FcepsilonRI interaction and reacts with receptor-bound IgE J Allergy Clin Immunol. 2001 Sep;108(3):409-16.
8: Zhang K, Liu J, Truong T, Zukin E, Chen W, Saxon A. Blocking Allergic Reaction through Targeting Surface-Bound IgE with Low-Affinity Anti-IgE Antibodies J Immunol. 2017 May 15;198(10):3823-3834.
9: Meng YG, Singh N, Wong WL. Binding of cynomolgus monkey IgE to a humanized anti-human IgE antibody and human high affinity IgE receptor Mol Immunol. 1996 May-Jun;33(7-8):635-42.
10: Laffer S, Lupinek C, Rauter I, Kneidinger M, Drescher A, Jordan JH, Krauth MT, Valent P, Kricek F, Spitzauer S, Englund H, Valenta R. A high-affinity monoclonal anti-IgE antibody for depletion of IgE and IgE-bearing cells Allergy. 2008 Jun;63(6):695-702.

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