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5-Chloro-2′-deoxyuridine (Highly Pure)

$395.00

Catalog Number: B2012300 (5 mg)
5-Chloro-2′-deoxyuridine (Highly Pure) is a high quality 5-chloro-2′-deoxy-uridine (CldU). This product has been used as molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request.

Live enquiry about this product via Text/SMS: 1-858-900-3210.

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SKU: B2012300 Categories: , Tag:

Description

5-Chloro-2′-deoxyuridine (Highly Pure)
Catalog number: B2012300
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 5 mg
Molecular Weight or Concentration: 262.6 g/mol
Supplied as: Crystals
Applications: molecular tool for various biochemical applications
Storage: -20C
Keywords: Chlorodeoxyuridine, CldU
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Brandon ML, Mi L, Chaung W, Teebor G, Boorstein RJ. 5-chloro-2′-deoxyuridine cytotoxicity results from base excision repair of uracil subsequent to thymidylate synthase inhibition Mutat Res. 2000 Mar 20;459(2):161-9.
2: Yamada K, Semba R, Ding X, Ma N, Nagahama M. Discrimination of cell nuclei in early S-phase, mid-to-late S-phase, and G(2)/M-phase by sequential administration of 5-bromo-2′-deoxyuridine and 5-chloro-2′-deoxyuridine J Histochem Cytochem. 2005 Nov;53(11):1365-70.
3: Hale JT, Bigelow JC, Mathews LA, McCormack JJ. Analytical and pharmacokinetic studies with 5-chloro-2′-deoxycytidine Biochem Pharmacol. 2002 Nov 15;64(10):1493-502.
4: Hoheisel JD, Lehrach H. Quantitative measurements on the duplex stability of 2,6-diaminopurine and 5-chloro-uracil nucleotides using enzymatically synthesized oligomers FEBS Lett. 1990 Nov 12;274(1-2):103-6.
5: Yennek S, Tajbakhsh S. DNA asymmetry and cell fate regulation in stem cells Semin Cell Dev Biol. 2013 Aug-Sep;24(8-9):627-42.
6: Pivazyan AD, Birks EM, Wood TG, Lin TS, Prusoff WH. Inhibition of poly(ADP-ribose)polymerase activity by nucleoside analogs of thymidine Biochem Pharmacol. 1992 Sep 1;44(5):947-53.
7: Smee DF, Humphreys DE, Hurst BL, Barnard DL. Antiviral activities and phosphorylation of 5-halo-2′-deoxyuridines and N-methanocarbathymidine in cells infected with vaccinia virus Antivir Chem Chemother. 2008;19(1):15-24.
8: Liu W. Single Molecular Resolution to Monitor DNA Replication Fork Dynamics upon Stress by DNA Fiber Assay Bio Protoc. 2021 Dec 20;11(24):e4269.
9: Eremeeva E, Abramov M, Marlière P, Herdewijn P. The 5-chlorouracil:7-deazaadenine base pair as an alternative to the dT:dA base pair Org Biomol Chem. 2016 Dec 20;15(1):168-176.
10: Rivero CW, Britos CN, Lozano ME, Sinisterra JV, Trelles JA. Green biosynthesis of floxuridine by immobilized microorganisms FEMS Microbiol Lett. 2012 Jun;331(1):31-6.

Products Related to 5-Chloro-2′-deoxyuridine (Highly Pure) can be found at Chemicals

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