Uricase from Arthrobacter globiformis

Product Description

Uricase from Arthrobacter globiformis
Catalog number: B2014026
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 100 units
Molecular Weight or Concentration: ~32 kDa – 15-30 units/mg protein
Supplied as: Powder
Applications: molecular tool for various biochemical applications
Storage: −20°C
Keywords: Urate oxidase, Urate:O2 oxidoreductase
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Suzuki K, Sakasegawa S, Misaki H, Sugiyama M. Molecular cloning and expression of uricase gene from Arthrobacter globiformis in Escherichia coli and characterization of the gene product J Biosci Bioeng. 2004;98(3):153-8.
2: Yang B, Kwon I. Thermostable and Long-Circulating Albumin-Conjugated Arthrobacter globiformis Urate Oxidase Pharmaceutics. 2021 Aug 19;13(8):1298.
3: Juan EC, Hoque MM, Shimizu S, Hossain MT, Yamamoto T, Imamura S, Suzuki K, Tsunoda M, Amano H, Sekiguchi T, Taknaka A. Structures of Arthrobacter globiformis urate oxidase-ligand complexes Acta Crystallogr D Biol Crystallogr. 2008 Aug;D64(Pt 8):815-22.
4: Shi Y, Wang T, Zhou XE, Liu QF, Jiang Y, Xu HE. Structure-based design of a hyperthermostable AgUricase for hyperuricemia and gout therapy Acta Pharmacol Sin. 2019 Oct;40(10):1364-1372.
5: Abdul Aziz SFN, Rahim ASMA, Normi YM, Alang Ahmad SA, Salleh AB. Rational design of mini protein mimicking uricase: Encapsulation in ZIF-8 for uric acid detection Proteins. 2023 Mar 13.
6: Zhang Z, Fu N, Li Q, Quan J. Development of a novel anti-inflammatory recombinant uricase with extended half-life for gout therapy Biochem Biophys Res Commun. 2023 May 8;666:115-121.
7: Kim WK, Patterson PH. Production of an egg yolk antibody specific to microbial uricase and its inhibitory effects on uricase activity Poult Sci. 2003 Oct;82(10):1554-8.
8: Feng J, Wang L, Liu H, Yang X, Liu L, Xie Y, Liu M, Zhao Y, Li X, Wang D, Zhan CG, Liao F. Crystal structure of Bacillus fastidious uricase reveals an unexpected folding of the C-terminus residues crucial for thermostability under physiological conditions Appl Microbiol Biotechnol. 2015 Oct;99(19):7973-86.
9: Yang B, Kwon I. Chemical Modification of Cysteine with 3-Arylpropriolonitrile Improves the In Vivo Stability of Albumin-Conjugated Urate Oxidase Therapeutic Protein Biomedicines. 2021 Sep 27;9(10):1334.
10: Zhang P, Lu X, Li Q, Lin X, Liu H, Ma X. [Cloning and characterization of a thermostable urate oxidase from Microbacterium sp. strain ZZJ4-1] Sheng Wu Gong Cheng Xue Bao. 2012 Jul;28(7):813-22.

Products Related to Uricase from Arthrobacter globiformis can be found at Enzymes