Tris (2-carboxyethyl) phosphine hydrochloride


Catalog Number: B2010710 (1 g)
Tris (2-carboxyethyl) phosphine hydrochloride (High Purity) is a highly pure crystalline Tris(2-carboxyethyl)phosphine hydrochloride. This product has been used as highly effective reducer of disulfide bonds. It has also been used in a wide array of other biochemical and immunological applications. Custom bulk amounts of this product are available upon request.

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SKU: B2010710 Categories: ,


Tris (2-carboxyethyl) phosphine hydrochloride (High Purity)
Catalog number: B2010710
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 1 g
Molecular Weight or Concentration: na
Supplied as: Powder
Applications: highly effective reducer of disulfide bonds
Storage: -20C
Keywords: TCEP
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

1: Zeng Y, Shinada K, Hano K, Sui L, Yang T, Li X, Himaki T. Effects of tris (2-carboxyethyl) phosphine hydrochloride treatment on porcine oocyte in vitro maturation and subsequent in vitro fertilized embryo developmental capacity Theriogenology. 2021 Mar 1;162:32-41.
2: Wu R, Jiang LP, Zhu JJ, Liu J. Effects of Small Molecules on DNA Adsorption by Gold Nanoparticles and a Case Study of Tris(2-carboxyethyl)phosphine (TCEP) Langmuir. 2019 Oct 15;35(41):13461-13468.
3: Dieguez-Acuña FJ, Woods JS. Inhibition of NF-kappaB-DNA binding by mercuric ion: utility of the non-thiol reductant, tris(2-carboxyethyl)phosphine hydrochloride (TCEP), on detection of impaired NF-kappaB-DNA binding by thiol-directed agents Toxicol In Vitro. 2000 Feb;14(1):7-16.
4: Fischer WH, Rivier JE, Craig AG. In situ reduction suitable for matrix-assisted laser desorption/ionization and liquid secondary ionization using tris(2-carboxyethyl)phosphine Rapid Commun Mass Spectrom. 1993 Mar;7(3):225-8.
5: Sato Y, Uchiki T, Iwama M, Kishimoto Y, Takahashi R, Ishigami A. Determination of dehydroascorbic acid in mouse tissues and plasma by using tris(2-carboxyethyl)phosphine hydrochloride as reductant in metaphosphoric acid/ethylenediaminetetraacetic acid solution Biol Pharm Bull. 2010;33(3):364-9.
6: Lykkesfeldt J. Determination of ascorbic acid and dehydroascorbic acid in biological samples by high-performance liquid chromatography using subtraction methods: reliable reduction with tris[2-carboxyethyl]phosphine hydrochloride Anal Biochem. 2000 Jun 15;282(1):89-93.
7: Dadouch M, Ladner Y, Bich C, Montels J, Morel J, Bechara C, Perrin C. In-capillary (electrophoretic) digestion-reduction-separation: A smart tool for middle-up analysis of mAb J Chromatogr A. 2021 Jul 5;1648:462213.
8: Reolo MJY, Eleazar CSR, Sonio JP, Solon RT, Villamor JLB, Loedin AK, Moore KJM. Saliva “Treat-and-Heat” Triplex Reverse Transcription Loop-Mediated Isothermal Amplification Assay for SARS-CoV-2 J Biomol Tech. 2021 Sep;32(3):186-198.
9: Li H, Cai T, Ren Y, Huang J, Jiang H, Hou Y, Tang C, Yang J, Zhao J, Yu P. A simple unlabeled human chorionic gonadotropin biosensor based on a peptide aptamer Anal Methods. 2021 Oct 8;13(38):4442-4451.
10: Tarlycheva AA, Markova ZG, Yurchenko DA, Shilova NV. Optimization of the sperm processing protocol for subsequent molecular cytogenetic studies Klin Lab Diagn. 2021 Oct 18;66(10):603-609.

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