Trans-trans-Farnesyl Pyrophosphate Ammonium Salt

Description

Trans-trans-Farnesyl Pyrophosphate Ammonium Salt
Catalog number: B2013746
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 5 mg
Molecular Weight or Concentration: 382.33 g/mol
Supplied as: Solid
Applications: molecular tool for various biochemical applications
Storage: -20°C
Keywords: (E,E)-3,7,11-Trimethyl-2,6,10-dodecatrien-1-yl pyrophosphate ammonium salt, Farnesyl diphosphate ammonium salt
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: POPJAK G, CORNFORTH JW, CORNFORTH RH, RYHAGE R, GOODMAN DS. Studies on the biosynthesis of cholesterol. XVI. Chemical synthesis of 1-H2-3-2-C-14- and 1-D2-2-C-14-trans-trans-farnesyl pyrophosphate and their utilization in squalene biosynthesis J Biol Chem. 1962 Jan;237:56-61.
2: Ericsson J, Thelin A, Chojnacki T, Dallner G. Substrate specificity of cis-prenyltransferase in rat liver microsomes J Biol Chem. 1992 Sep 25;267(27):19730-5.
3: Croteau R, Gundy A. Cyclization of farnesyl pyrophosphate to the sesquiterpene olefins humulene and caryophyllene by an enzyme system from sage (Salvia officinalis) Arch Biochem Biophys. 1984 Sep;233(2):838-41.
4: Roullet JB, Xue H, Chapman J, McDougal P, Roullet CM, McCarron DA. Farnesyl analogues inhibit vasoconstriction in animal and human arteries J Clin Invest. 1996 May 15;97(10):2384-90.
5: Ericsson J, Thelin A, Chojnacki T, Dallner G. Characterization and distribution of cis-prenyl transferase participating in liver microsomal polyisoprenoid biosynthesis Eur J Biochem. 1991 Dec 18;202(3):789-96.
6: Cane DE, Yang G, Xue Q, Shim JH. Trichodiene synthase. Substrate specificity and inhibition Biochemistry. 1995 Feb 28;34(8):2471-9.
7: Tanaka Y, Kawahara S, Eng AH, Takei A, Ohya N. Structure of cis-polyisoprene from Lactarius mushrooms Acta Biochim Pol. 1994;41(3):303-9.
8: Noel JP, Dellas N, Faraldos JA, Zhao M, Hess BA Jr, Smentek L, Coates RM, O’Maille PE. Structural elucidation of cisoid and transoid cyclization pathways of a sesquiterpene synthase using 2-fluorofarnesyl diphosphates ACS Chem Biol. 2010 Apr 16;5(4):377-92.
9: Cane DE, Pawlak JL, Horak RM. Studies of the cryptic allylic pyrophosphate isomerase activity of trichodiene synthase using the anomalous substrate 6,7-dihydrofarnesyl pyrophosphate Biochemistry. 1990 Jun 12;29(23):5476-90.
10: Fujihashi M, Zhang YW, Higuchi Y, Li XY, Koyama T, Miki K. Crystal structure of cis-prenyl chain elongating enzyme, undecaprenyl diphosphate synthase Proc Natl Acad Sci U S A. 2001 Apr 10;98(8):4337-42.

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