Tissue Plasminogen Activator (human)


Catalog Number: B2010513 (100 ug)
Tissue plasminogen activator (human) is a highly pure protease of the S1 trypsin family found in many mammalian tissues. This product has been used as molecular tool. It has also been used in a wide array of other biochemical and immunological applications. Custom bulk amounts of this product are available upon request.

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Tissue plasminogen activator (human)
Catalog number: B2010513
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 100 ug
Molecular Weight or Concentration: 70 kDa
Supplied as: Powder
Storage: −20°C
Keywords: tPA
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

1: Kruithof EK, Dunoyer-Geindre S. Human tissue-type plasminogen activator.
Thromb Haemost. 2014 Aug;112(2):243-54.

2: Loscalzo J, Braunwald E. Tissue plasminogen activator. N Engl J Med. 1988 Oct

3: Amiri M, Jalali-Javaran M, Haddad R, Ehsani P. In silico and in vivo analyses
of the mutated human tissue_plasminogen_activator (mtPA) and the antithetical
effects of P19 silencing suppressor on its expression in two Nicotiana species.
Sci Rep. 2018 Sep 19;8(1):14079.

4: Thiebaut AM, Gauberti M, Ali C, Martinez De Lizarrondo S, Vivien D, Yepes M,
Roussel BD. The role of plasminogen activators in stroke treatment: fibrinolysis
and beyond. Lancet Neurol. 2018 Dec;17(12):1121-1132.

5: Jensen PJ, Baird J, Belin D, Vassalli JD, Busso N, Gubler P, Lazarus GS.
Tissue_plasminogen_activator in psoriasis. J Invest Dermatol. 1990 Nov;95(5

6: Vogl T, Hinz HJ. Characterization of recombinant proteins: biochemical and
biophysical criteria for the identity of native and renatured human tissue_plasminogen_activator and its mutants. Biotechnol Appl Biochem. 1994

7: Tripathi RC, Park JK, Tripathi BJ, Millard CB. Tissue_plasminogen_activator
in human aqueous humor and its possible therapeutic significance. Am J
Ophthalmol. 1988 Dec 15;106(6):719-22.

8: Diamond MP, El-Hammady E, Wang R, Kruger M, Saed G. Regulation of expression
of tissue_plasminogen_activator and plasminogen activator inhibitor-1 by
dichloroacetic acid in human fibroblasts from normal peritoneum and adhesions.
Am J Obstet Gynecol. 2004 Apr;190(4):926-34.
9: Hayes BD. Calculated Decisions: tPA (Tissue Plasminogen Activator) Dosing for
Stroke Calculator. Emerg Med Pract. 2019 Jun 24;21(6):CD8-CD9.

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