Thymic Stromal Lymphopoietin (Human, Recombinant)

Product Description

Thymic Stromal Lymphopoietin (Human, Recombinant)
Catalog number: B2010325
Lot number: Batch Dependent
Expiration Date: Batch dependent
Volume/Weight: 10 ug
pH: 7.4 upon reconstitution
Supplied as: Lyophilized Powder
Appearance: Powder
Applications: highly pure Thymic Stromal Lymphopoietin (Human, Recombinant) expressed in E. coli. This protein acts as an epithelial cell-derived cytokine that plays key role in allergic inflammation.
Storage: -20C
Keywords: rHuTSLP; TSLP
Grade: Biotechnology grade. All components are highly pure (minimum 95%). All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: He R, Geha RS. Thymic stromal_lymphopoietin. Ann N Y Acad Sci. 2010
Jan;1183:13-24.

2: Guo H, Ji X, Yang G, Jin Y. Abnormal thymic stromal_lymphopoietin expression
in the gastrointestinal mucosa of patients with eosinophilic gastroenteritis. J
Pediatr (Rio J). 2020 May-Jun;96(3):350-355.

3: Ye L, Schnepf D, Becker J, Ebert K, Tanriver Y, Bernasconi V, Gad HH,
Hartmann R, Lycke N, Staeheli P. Interferon-λ enhances adaptive mucosal immunity
by boosting release of thymic_stromal lymphopoietin. Nat Immunol. 2019
May;20(5):593-601.
30886417.

4: Lin SC, Cheng FY, Liu JJ, Ye YL. Expression and Regulation of Thymic_Stromal
Lymphopoietin and Thymic Stromal Lymphopoietin Receptor Heterocomplex in the
Innate-Adaptive Immunity of Pediatric Asthma. Int J Mol Sci. 2018 Apr
18;19(4):1231.

5: Lo Kuan E, Ziegler SF. Thymic stromal lymphopoietin and cancer. J Immunol.
2014 Nov 1;193(9):4283-8.

6: Zhang ZD, Deng YX, Ma HX, Chen XG, Chen LH, Qu J. Thymic_Stromal
Lymphopoietin-Related Allergic Pathway in Patients With Vernal
Keratoconjunctivitis. Cornea. 2019 Mar;38(3):344-351.

7: Ojanguren I, Martin JG, Lemiere C. Thymic Stromal_Lymphopoietin: A Promising
Target in the Treatment of Asthma? Arch Bronconeumol. 2017 Oct;53(10):545-546.
English, Spanish.
8: Liu S, Verma M, Michalec L, Liu W, Sripada A, Rollins D, Good J, Ito Y, Chu
H, Gorska MM, Martin RJ, Alam R. Steroid resistance of airway type 2 innate
lymphoid cells from patients with severe asthma: The role of thymic stromal
lymphopoietin. J Allergy Clin Immunol. 2018 Jan;141(1):257-268.e6.

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