TCPTP Protein

Description

TCPTP Protein
Catalog number: B2013681
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 10 μg
Molecular Weight or Concentration: 39.7 kDa
Supplied as: Solution
Applications: molecular tool for various biochemical applications
Storage: -20°C
Keywords: TCPTP Protein
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Grohmann M, Wiede F, Dodd GT, Gurzov EN, Ooi GJ, Butt T, Rasmiena AA, Kaur S, Gulati T, Goh PK, Treloar AE, Archer S, Brown WA, Muller M, Watt MJ, Ohara O, McLean CA, Tiganis T. Obesity Drives STAT-1-Dependent NASH and STAT-3-Dependent HCC Cell. 2018 Nov 15;175(5):1289-1306.e20.
2: Spalinger MR, Sayoc-Becerra A, Santos AN, Shawki A, Canale V, Krishnan M, Niechcial A, Obialo N, Scharl M, Li J, Nair MG, McCole DF. PTPN2 Regulates Interactions Between Macrophages and Intestinal Epithelial Cells to Promote Intestinal Barrier Function Gastroenterology. 2020 Nov;159(5):1763-1777.e14.
3: Song J, Lan J, Tang J, Luo N. PTPN2 in the Immunity and Tumor Immunotherapy: A Concise Review Int J Mol Sci. 2022 Sep 2;23(17):10025.
4: Wang YN, Liu S, Jia T, Feng Y, Zhang W, Xu X, Zhang D. T Cell Protein Tyrosine Phosphatase in Osteoimmunology Front Immunol. 2021 Feb 22;12:620333.
5: Singh JP, Li Y, Chen YY, Hsu SD, Page R, Peti W, Meng TC. The catalytic activity of TCPTP is auto-regulated by its intrinsically disordered tail and activated by Integrin alpha-1 Nat Commun. 2022 Jan 10;13(1):94.
6: Wang YN, Liu S, Jia T, Feng Y, Xu X, Zhang D. T Cell Protein Tyrosine Phosphatase in Glucose Metabolism Front Cell Dev Biol. 2021 Jun 29;9:682947.
7: Spalinger MR, Sayoc-Becerra A, Ordookhanian C, Canale V, Santos AN, King SJ, Krishnan M, Nair MG, Scharl M, McCole DF. The JAK Inhibitor Tofacitinib Rescues Intestinal Barrier Defects Caused by Disrupted Epithelial-macrophage Interactions J Crohns Colitis. 2021 Mar 5;15(3):471-484.
8: Tang C, Feng W, Bao Y, Du H. Long non-coding RNA TINCR promotes hepatocellular carcinoma proliferation and invasion via STAT3 signaling by direct interacting with T-cell protein tyrosine phosphatase (TCPTP) Bioengineered. 2021 Dec;12(1):2119-2131.
9: Ylilauri M, Mattila E, Nurminen EM, K_pyl_ J, Niinivehmas SP, M__tt_ JA, Pentik_inen U, Ivaska J, Pentik_inen OT. Molecular mechanism of T-cell protein tyrosine phosphatase (TCPTP) activation by mitoxantrone Biochim Biophys Acta. 2013 Oct;1834(10):1988-97.
10: Debarba LK, Vechiato FMV, Veida-Silva H, Borges BC, Jamur MC, Antunes-Rodrigues J, Elias LLK. The role of TCPTP on leptin effects on astrocyte morphology Mol Cell Endocrinol. 2019 Feb 15;482:62-69.

Products Related to TCPTP Protein can be found at Proteins