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Recombinant Human IL-2 Protein

Original price was: $1,395.00.Current price is: $695.00.

Catalog Number: B2015591 (5 μg)
Recombinant Human IL-2 Protein is a high quality Recombinant Human IL-2 Protein. This product has been used as a molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request.

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Product Description

Recombinant Human IL-2 Protein
Catalog number: B2015591
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 5 μg
Molecular Weight or Concentration: 16 kDa
Supplied as: Solution
Applications: a molecular tool for various biochemical applications
Storage: -20°C
Keywords: IL 2, IL2, IL-2, interleukin 2, lymphokine, T cell growth factor, TCGF
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Silva DA. An IL-2 Protein Therapeutic for Cancer that Gains Function on the Spot Cancer Immunol Res. 2022 May 3;10(5):544.
2: Ward NC, Lui JB, Hernandez R, Yu L, Struthers M, Xie J, Santos Savio A, Dwyer CJ, Hsiung S, Yu A, Malek TR. Persistent IL-2 Receptor Signaling by IL-2/CD25 Fusion Protein Controls Diabetes in NOD Mice by Multiple Mechanisms Diabetes. 2020 Nov;69(11):2400-2413.
3: Bruton JK, Koeller JM. Recombinant interleukin-2 Pharmacotherapy. 1994 Nov-Dec;14(6):635-56.
4: Fleischmann JD, Wentworth D, Valencic F, Imbembo AL, Koehler KA. Interleukin-2 self-association Biochem Biophys Res Commun. 1988 Apr 29;152(2):879-85.
5: Chou SH, Shetty AV, Geng Y, Xu L, Munirathinam G, Pipathsouk A, Tan I, Morris T, Wang B, Chen A, Zheng G. Palmitate-derivatized human IL-2: a potential anticancer immunotherapeutic of low systemic toxicity Cancer Immunol Immunother. 2013 Mar;62(3):597-603.
6: Foss FM. DAB(389)IL-2 (denileukin diftitox, ONTAK): a new fusion protein technology Clin Lymphoma. 2000 Nov;1 Suppl 1:S27-31.
7: Peraino JS, Zhang H, Rajasekera PV, Wei M, Madsen JC, Sachs DH, Huang CA, Wang Z. Diphtheria toxin-based bivalent human IL-2 fusion toxin with improved efficacy for targeting human CD25(+) cells J Immunol Methods. 2014 Mar;405:57-66.
8: Knezević M, Vorauer-Uhl K, Hohenwarter O, Steindl F, Grabherr R, Raspor P. Human interleukin-2 (IL-2) expressed by transfected mammalian cells Pflugers Arch. 1996;431(6 Suppl 2):R227-8.
9: Pillet AH, Juffroy O, Mazard-Pasquier V, Moreau JL, Gesbert F, Chastagner P, Colle JH, Thèze J, Rose T. Human IL-Rbeta chains form IL-2 binding homodimers Eur Cytokine Netw. 2008 Mar;19(1):49-59.
10: Prümmer O. Treatment-induced antibodies to interleukin-2 Biotherapy. 1997;10(1):15-24.

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Additional Information

Weight 48 oz
Dimensions 8 × 8 × 8 in

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