Recombinant Holo Lactoferrin


Catalog Number: B2012222 (100 ug)
Recombinant Holo Lactoferrin is a high quality Recombinant Holo Lactoferrin expressed in Oryza sativa. This product has been used as molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request.

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Recombinant Holo Lactoferrin
Catalog number: B2012222
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 100 ug
Molecular Weight or Concentration: 80 kDa
Supplied as: Lyophilized
Applications: molecular tool for various biochemical applications
Storage: -20°C
Keywords: LF, lactotransferrin, LTF
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

1: Zhang Z, Lu M, Chen C, Tong X, Li Y, Yang K, Lv H, Xu J, Qin L. Holo-lactoferrin: the link between ferroptosis and radiotherapy in triple-negative breast cancer Theranostics. 2021 Jan 1;11(7):3167-3182.
2: Zhang Z, Yang J, Min Q, Ling C, Maiti D, Xu J, Qin L, Yang K. Holo-Lactoferrin Modified Liposome for Relieving Tumor Hypoxia and Enhancing Radiochemotherapy of Cancer Small. 2019 Feb;15(6):e1803703.
3: Rodriguez-Ochoa N, Cortes-Reynosa P, Rodriguez-Rojas K, de la Garza M, Salazar EP. Bovine holo-lactoferrin inhibits migration and invasion in MDA-MB-231 breast cancer cells Mol Biol Rep. 2022 Nov 1.
4: Mikulic N, Uyoga MA, Mwasi E, Stoffel NU, Zeder C, Karanja S, Zimmermann MB. Iron Absorption is Greater from Apo-Lactoferrin and is Similar Between Holo-Lactoferrin and Ferrous Sulfate: Stable Iron Isotope Studies in Kenyan Infants J Nutr. 2020 Dec 10;150(12):3200-3207.
5: Lönnerdal B. Lactoferrin receptors in intestinal brush border membranes Adv Exp Med Biol. 1994;357:171-5.
6: Shibuya N, Yoshikawa Y, Watanabe K, Ohtsuka H, Orino K. Iron-dependent binding of bovine milk α-casein with holo-lactoferrin, but not holo-transferrin Biometals. 2012 Oct;25(5):1083-8.
7: Ortíz-Estrada G, Luna-Castro S, Piña-Vázquez C, Samaniego-Barrón L, León-Sicairos N, Serrano-Luna J, de la Garza M. Iron-saturated lactoferrin and pathogenic protozoa: could this protein be an iron source for their parasitic style of life? Future Microbiol. 2012 Jan;7(1):149-64.
8: Lopez V, Kelleher SL, Lonnerdal B. Lactoferrin receptor mediates apo- but not holo-lactoferrin internalization via clathrin-mediated endocytosis in trophoblasts Biochem J. 2008 Apr 15;411(2):271-8.
9: Zarzosa-Moreno D, Avalos-Gómez C, Ramírez-Texcalco LS, Torres-López E, Ramírez-Mondragón R, Hernández-Ramírez JO, Serrano-Luna J, de la Garza M. Lactoferrin and Its Derived Peptides: An Alternative for Combating Virulence Mechanisms Developed by Pathogens Molecules. 2020 Dec 8;25(24):5763.
10: Lu J, Haley KP, Francis JD, Guevara MA, Doster RS, Craft KM, Moore RE, Chambers SA, Delgado AG, Piazuelo MB, Damo SM, Townsend SD, Gaddy JA. The Innate Immune Glycoprotein Lactoferrin Represses the Helicobacter pylori cag Type IV Secretion System Chembiochem. 2021 Sep 14;22(18):2783-2790.

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