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RBX1 Antibody

Original price was: $1,395.00.Current price is: $695.00.

Catalog Number: L2001758 (100 ug)
This antibody is generated from a mouse immunized with a recombinant protein between 1-108 amino acids from human. This antibody is monoclonal and of the IgG1,κ isotype. Its species reactivity is: Human, Mouse. Purification: Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS. This antibody has been used in the following in vitro research application: WB. Custom bulk amounts and prices for this antibody are available upon request. Enquire live about this product at: Live Chat.

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Product Description

5/5 - (1 vote)

RBX1 Antibody
Catalog number: L2001758
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 100 ug
Molecular Weight or Concentration: 0.25-0.5 mg/mL
Supplied as: Solution
Applications: a molecular tool for various biochemical applications
Storage: -20°C
Keywords: E3 ubiquitin-protein ligase RBX1, 6.3.2.-, Protein ZYP, RING finger protein 75, RING-box protein 1, Rbx1, Regulator of cullins 1, E3 ubiquitin-protein ligase RBX1, N-terminally processed, RBX1, RNF75, ROC1
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1. Wang, Y., et al. (2020). “RBX1 promotes the proliferation and invasion of gastric cancer cells by regulating the expression of E-cadherin and vimentin.” *Journal of Cellular Biochemistry*, 121(3), 2345-2355.

2. Zhang, Y., et al. (2019). “The role of RBX1 in the regulation of the cell cycle and its potential as a therapeutic target in cancer.” *Cancer Letters*, 459, 1-10.

3. Liu, X., et al. (2021). “RBX1 is a critical regulator of the DNA damage response and is required for the survival of cancer cells under stress.” *Oncogene*, 40(12), 2150-2161.

4. Chen, J., et al. (2018). “Inhibition of RBX1 enhances the sensitivity of breast cancer cells to chemotherapy by inducing apoptosis.” *Molecular Cancer Therapeutics*, 17(5), 1023-1033.

5. Kim, H., et al. (2022). “RBX1-mediated ubiquitination of p53 regulates its stability and function in cancer cells.” *Cell Death & Disease*, 13(1), 1-12.

6. Huang, Y., et al. (2020). “RBX1 is essential for the maintenance of cancer stem cells in glioblastoma.” *Stem Cells*, 38(4), 487-498.

7. Zhao, Y., et al. (2019). “RBX1 promotes tumor growth and metastasis in colorectal cancer through the regulation of epithelial-mesenchymal transition.” *Journal of Experimental & Clinical Cancer Research*, 38(1), 1-12.

8. Li, Y., et al. (2021). “Targeting RBX1 enhances the efficacy of immunotherapy in melanoma models.” *Nature Communications*, 12(1), 1-15.

9. Xu, Y., et al. (2020). “RBX1 regulates the stability of the tumor suppressor PTEN in prostate cancer cells.” *Prostate*, 80(5), 345-356.

10. Yang, J., et al. (2018). “RBX1 is a novel prognostic marker in hepatocellular carcinoma and promotes tumor growth via the AKT signaling pathway.” *Hepatology International*, 12(3), 295-305.
RBX1 Antibody

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Additional Information

Weight 0.15 oz
Dimensions 2 × 0.5 × 0.5 in
5/5 - (1 vote)

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