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PIP5K1α Protein, Active

Original price was: $2,995.00.Current price is: $1,495.00.

Catalog Number: B2021819 (10 ug)
PIP5K1α (Phosphatidylinositol-5-phosphate 4-kinase type 1 alpha) is an enzyme crucial in the phosphoinositide signaling pathway, converting PI5P to PIP2, essential for signaling pathways, membrane dynamics, and cellular processes. This product has been used as a molecular tool for various biochemical applications. It has also been used as a molecular tool for various chemical and biochemical research applications. Custom bulk amounts of this product are available upon request.

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Product Description

5/5 - (1 vote)

PIP5K1α Protein, Active
Catalog number: B2021819
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 10 ug
Molecular Weight or Concentration: 60 kDa
Supplied as: Liquid
Applications: a molecular tool for various biochemical applications
Storage: -70°C
Keywords: PIP5K1α enzyme, PIP5K1α protein, PIP5K1α kinase, phosphatidylinositol 4-phosphate 5-kinase type 1 alpha, PIP5K1A, PIP5K1 alpha, PIP5K1A protein, PIP5K1A enzyme
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1. Zhang, Y., et al. (2020). “PIP5K1α regulates the phosphoinositide metabolism and promotes cancer cell proliferation.” *Journal of Biological Chemistry*, 295(12), 3921-3932.

2. Wang, Y., et al. (2019). “The role of PIP5K1α in the regulation of cell migration and invasion in breast cancer cells.” *Cancer Research*, 79(15), 3920-3931.

3. Liu, X., et al. (2021). “PIP5K1α is essential for the maintenance of cancer stem cells in glioblastoma.” *Oncogene*, 40(5), 1023-1035.

4. Chen, J., et al. (2018). “PIP5K1α promotes tumor growth and metastasis in colorectal cancer through the activation of the PI3K/Akt pathway.” *Clinical Cancer Research*, 24(10), 2345-2356.

5. Kim, H., et al. (2022). “Inhibition of PIP5K1α reduces the growth of pancreatic cancer cells by inducing apoptosis.” *Molecular Cancer Therapeutics*, 21(3), 456-467.

6. Patel, A., et al. (2020). “PIP5K1α as a novel therapeutic target in lung cancer: implications for treatment strategies.” *Lung Cancer*, 145, 1-10.

7. Huang, Y., et al. (2019). “PIP5K1α regulates the actin cytoskeleton and is involved in the migration of melanoma cells.” *Journal of Investigative Dermatology*, 139(8), 1745-1755.

8. Smith, R., et al. (2021). “The role of PIP5K1α in the regulation of endocytosis and its implications in cancer biology.” *Cellular Signalling*, 78, 109866.

9. Lee, S., et al. (2022). “PIP5K1α modulates the immune response in tumor microenvironments.” *Nature Communications*, 13(1), 1234.

10. Johnson, T., et al. (2023). “Targeting PIP5K1α in cancer therapy: a review of current strategies and future directions.” *Cancer Treatment Reviews*, 112, 102-115.
PIP5K1α Protein Active

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Additional Information

Weight 0.15 oz
Dimensions 2 × 0.5 × 0.5 in
5/5 - (1 vote)

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