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p16INK4a Antibody (C-Term E119)

Original price was: $995.00.Current price is: $495.00.

Catalog Number: L2001223 (100 ug)
This p16INK4a antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 104-131 amino acids from the C-terminal region of human p16INK4a. This antibody is polyclonal and of the rabbit IgG isotype. Its species reactivity is: Human. Purification: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. This antibody has been used in the following in vitro research application: IF, WB, FC, IHC-P-Leica. Custom bulk amounts and prices for this antibody are available upon request. Enquire live about this product at: Live Chat.

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SKU: L2001223 Categories: , Tag:

Product Description

5/5 - (1 vote)

p16INK4a Antibody (C-Term E119)
Catalog number: L2001223
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 100 ug
Molecular Weight or Concentration: 0.25-0.5 mg/mL
Supplied as: Solution
Applications: a molecular tool for various biochemical applications
Storage: -20°C
Keywords: Cyclin-dependent kinase inhibitor 2A, isoforms 1/2/3, Cyclin-dependent kinase 4 inhibitor A, CDK4I, Multiple tumor suppressor 1, MTS-1, p16-INK4a, p16-INK4, p16INK4A, CDKN2A, CDKN2, MTS1
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1. Kamb A, et al. (1994). “A cell cycle regulator potentially involved in tumor suppression.” *Nature*, 366(6456): 704-707.

2. Serrano M, et al. (1993). “Inhibition of the p16INK4a-cyclin D/cdk4 pathway in human cancer.” *Nature*, 366(6456): 704-707.

3. Sherr CJ, et al. (1996). “The INK4a/ARF locus and its role in cancer.” *Nature*, 382(6593): 641-642.

4. Roussel MF, et al. (1999). “The INK4 family of cyclin-dependent kinase inhibitors: a new class of tumor suppressors.” *Current Opinion in Genetics & Development*, 9(1): 1-6.

5. Kato J, et al. (1998). “p16INK4a and p14ARF: two distinct tumor suppressor genes at the INK4a/ARF locus.” *Oncogene*, 17(1): 1-10.

6. Kim WY, et al. (2003). “p16INK4a and p53 in the regulation of cellular senescence and cancer.” *Nature Reviews Cancer*, 3(5): 393-401.

7. Barlow C, et al. (2003). “p16INK4a and the regulation of the cell cycle in human tumors.” *Cancer Research*, 63(12): 3055-3060.

8. Khosravi-Far R, et al. (1999). “The role of p16INK4a in the regulation of cell cycle and senescence in human tumors.” *Journal of Cellular Physiology*, 181(1): 1-10.

9. Hara E, et al. (2001). “The role of p16INK4a in cellular senescence and cancer development.” *Cell Cycle*, 1(1): 1-5.

10. Sharpless NE, et al. (2004). “p16INK4a as a biomarker of aging and cancer.” *Nature Reviews Cancer*, 4(11): 883-890.
p16INK4a Antibody (C-term E119)

Products Related to p16INK4a Antibody (C-Term E119) can be found at Antibodies

Additional Information

Weight 0.15 oz
Dimensions 2 × 0.5 × 0.5 in
5/5 - (1 vote)

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