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MPO Antibody Polyclonal

Original price was: $595.00.Current price is: $295.00.

Catalog #: A2010027 (0.5 mg)
Polyclonal antibody to human Myeloperoxidase, a peroxidase enzyme mostly expressed in neutrophils, which produces hypohalous acids known for their antimicrobial activities. MPO is released in the blood when artery walls are damaged. Bulk pricing and biotinylation services are available.

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SKU: A2010027 Category: Tag:

Product Description

MPO Antibody Polyclonal

Catalog number: A2010027
Lot number: Batch Dependent
Expiration date: Batch Dependent
Package Size: 0.5 mg
Other names: Polyclonal antibody to human Myeloperoxidase (MPO)
Supplied as: Solution
Concentration: 1.0 mg/mL
Clonality: Polyclonal
Host: Rabbit
Specificity: Human Myeloperoxidase (MPO)
Cross-reaction: n/a
Purification: Affinity Purified
Immunogen High purity native human Myeloperoxidase
Preservative: 0.05% sodium azide
Storage: 2-8°C (short term), -20°C (long term). Avoid repeated freeze-thaw.

References

  • Myeloperoxidase. (2015). Encyclopedia of Immunotoxicology, 648–648.
  • Griffin, S. V., Chapman, P. T., Lianos, E. A., and Lockwood, C. M. (1999). The inhibition of myeloperoxidase by ceruloplasmin can be reversed by anti-myeloperoxidase antibodies. Kidney International, 55(3), 917–925.
  • Furtmüller, P. G., Obinger, C., Hsuanyu, Y., and Dunford, H. B. (2000). Mechanism of reaction of myeloperoxidase with hydrogen peroxide and chloride ion. European Journal of Biochemistry, 267(19), 5858–5864.
  • Dawra, R., Ku, Y., Sharif, R., Dhaulakhandi, D., and Saluja, A. (2004). Myeloperoxidase Inhibitory Activity In Pancreas And Lung—A Simple Method For Its Removal And Extraction Of Myeloperoxidase. Pancreas, 29(4), 362.
  • Ichimori, K., Fukuyama, N., Nakazawa, H., Aratani, Y., Koyama, H., Takizawa, S., Suzuki, K. (2003). Myeloperoxidase has Directly-opposed Effects on Nitration Reaction–Study on Myeloperoxidase-deficient Patient and Myeloperoxidase-knockout Mice. Free Radical Research, 37(5), 481–489.
  • Chen S, Chen H, Du Q, Shen J. Targeting Myeloperoxidase (MPO) Mediated
    Oxidative Stress and Inflammation for Reducing Brain Ischemia Injury: Potential
    Application of Natural Compounds. Front Physiol. 2020 May 19;11:433.
  • Ndrepepa G. Myeloperoxidase – A bridge linking inflammation and oxidative
    stress with cardiovascular disease. Clin Chim Acta. 2019 Jun;493:36-51.
  • Manchanda K, Kolarova H, Kerkenpaß C, Mollenhauer M, Vitecek J, Rudolph V,
    Kubala L, Baldus S, Adam M, Klinke A. MPO (Myeloperoxidase) Reduces Endothelial
    Glycocalyx Thickness Dependent on Its Cationic Charge. Arterioscler Thromb Vasc
    Biol. 2018 Aug;38(8):1859-1867.
  • Variji A, Shokri Y, Fallahpour S, Zargari M, Bagheri B, Abediankenari S,
    Alizadeh A, Mahrooz A. The combined utility of myeloperoxidase (MPO) and
    paraoxonase 1 (PON1) as two important HDL-associated enzymes in coronary artery
    disease: Which has a stronger predictive role? Atherosclerosis. 2019
    Jan;280:7-13.

Additional Information

Weight 32 oz
Dimensions 8 × 6.75 × 5.5 in

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