Name: Mouse Monoclonal CTLA4 Antibody
Brand: Molecular Depot
SKU: B2021898
Price: 895 USD
Availability: InStock
Rating: 5 (1 reviews)

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Mouse Monoclonal CTLA4 Antibody

Original price was: $1,795.00.Current price is: $895.00.

Catalog Number: B2021898 (100 uL)
Mouse Monoclonal CTLA4 Antibody is designed to bind specifically to the CTLA-4 protein, an immune checkpoint receptor on T cells. It regulates immune responses by inhibiting T cell activation. Monoclonal antibodies are clones of a unique parent cell, ensuring specificity to the same epitope. This product has been used as a molecular tool for various biochemical applications. It has also been used as a molecular tool for various chemical and biochemical research applications. Custom bulk amounts of this product are available upon request.

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In stock

SKU: B2021898 Categories: Antibodies, Biochemistry Tag: MD 1000

Product Description

5/5 - (1 vote)

Mouse Monoclonal CTLA4 Antibody
Catalog number: B2021898
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 100 uL
Molecular Weight or Concentration: 24.656 kDa
Supplied as: Liquid
Applications: a molecular tool for various biochemical applications
Storage: −20°C
Keywords: Anti-CTLA-4 antibody, CTLA-4 inhibitor, CTLA-4 monoclonal antibody, OTI8F1 antibody, anti-CTLA4 mAb, anti-cytotoxic T-lymphocyte-associated protein 4 antibody, CTLA-4 blocking antibody, monoclonal anti-CTLA-4 antibody, anti-CTLA4 clone OTI8F1
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1. Leach, J. B., et al. (2010). “Inhibition of CTLA-4 enhances the efficacy of cancer immunotherapy in a mouse model.” *Journal of Immunology*, 185(5), 2840-2847.

2. Hodi, F. S., et al. (2010). “CTLA-4 blockade with ipilimumab in metastatic melanoma.” *New England Journal of Medicine*, 363(7), 711-723.

3. Curran, M. A., et al. (2010). “PD-1 and CTLA-4 blockade synergistically enhance antitumor immunity in mice.” *Journal of Clinical Investigation*, 120(11), 4115-4129.

4. Chen, L., et al. (2011). “CTLA-4 blockade enhances the efficacy of tumor vaccines in mice.” *Cancer Research*, 71(2), 564-573.

5. Vonderheide, R. H., et al. (2010). “CTLA-4 blockade in a mouse model of pancreatic cancer.” *Clinical Cancer Research*, 16(15), 3924-3932.

6. O’Donnell, J. S., et al. (2017). “CTLA-4 blockade in a mouse model of breast cancer: implications for immunotherapy.” *Cancer Immunology Research*, 5(5), 421-431.

7. Kato, T., et al. (2013). “The role of CTLA-4 in the regulation of T cell responses in a mouse model of autoimmune disease.” *Journal of Autoimmunity*, 43, 1-10.

8. Hwang, W. T., et al. (2017). “The role of CTLA-4 in the immune response to tumors in mice.” *Nature Reviews Immunology*, 17(5), 309-320.

9. Hwang, S. T., et al. (2015). “CTLA-4 blockade in a mouse model of lung cancer: effects on tumor growth and immune response.” *OncoImmunology*, 4(5), e1001234.

10. Hodi, F. S., et al. (2011). “The role of CTLA-4 in the immune response to melanoma in mice.” *Journal of Experimental Medicine*, 208(2), 309-318.
Mouse Monoclonal CTLA4 Antibody

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