Lipoic Acid-Cyclodextrin-Complex

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Lipoic Acid-Cyclodextrin-Complex
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Lipoic Acid-Cyclodextrin-Complex

Original price was: $1,795.00.Current price is: $895.00.

Catalog Number: B2027438 (100 mg)
Lipoic Acid-Cyclodextrin Complex is a host-guest inclusion compound in which lipoic acid is encapsulated within a cyclic oligosaccharide cavity to enhance its aqueous solubility and structural stability. The cyclodextrin matrix protects the bioactive lipoic acid from heat, UV light, and acidic degradation, preventing unwanted polymerization. Custom bulk amounts of this product are available upon request.

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Product Description

5/5 - (2 votes)

Lipoic Acid-Cyclodextrin-Complex
Catalog number: B2027438
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 100 mg
Molecular Weight or Concentration: NA
Supplied as: Chemicals
Storage: RT
Keywords: Alpha-lipoic acid/cyclodextrin complex, Alpha-lipoic acid-cyclodextrin complex, ALA-cyclodextrin complex

References:
1. Ikuta, N., Sugiyama, H., Shimosegawa, H., Nakane, R., Ishida, Y., Uekaji, Y., Nakata, D., Pallauf, K., Rimbach, G., & Terao, K. (2013). Analysis of the physicochemical properties of R(+)-alpha lipoic acid-cyclodextrin complexes. International Journal of Molecular Sciences, 14(2), 3639-3655.
2. Takahashi, H., Bungo, Y., & Mikuni, K. (2011). The aqueous solubility and thermal stability of α-lipoic acid are enhanced by cyclodextrin. Journal of Inclusion Phenomena and Macrocyclic Chemistry, 69(1-2), 127-132.
3. Uchida, T., Ikeda, S., Ichikawa, T., Watanabe, T., Uekaji, Y., Nakata, D., & Terao, K. (2015). Bioavailability of an R-α-Lipoic Acid/γ-Cyclodextrin Complex in Healthy Volunteers. International Journal of Molecular Sciences, 16(9), 21781-21791.
4. Miljak, K., Radić, K., Galić, E., Špada, V., Vrban Đerek, L., Vianello, R., Vitali Čepo, D., & Jug, M. (2024). Encapsulation and Stabilization of α-Lipoic Acid in Cyclodextrin Inclusion Complexes. Pharmaceutics, 16(2), 245.
5. Zheng, X. Y., Zhang, Y. D., & Liu, J. (2017). Inclusion complex of α-lipoic acid containing alkalizer. Indian Journal of Pharmaceutical Sciences, 79(3), 421-428.
6. Loftsson, T., & Duchêne, D. (2007). Cyclodextrins and their pharmaceutical applications. International Journal of Pharmaceutics, 329(1-2), 1-11.
7. Szejtli, J. (1998). Introduction and general overview of cyclodextrin chemistry. Chemical Reviews, 98(5), 1743-1754.
8. Davis, M. E., & Brewster, M. E. (2004). Cyclodextrin-based pharmaceutics: past, present and future. Nature Reviews Drug Discovery, 3(12), 1023-1035.
9. Del Valle, E. M. (2004). Cyclodextrins and their uses: a review. Process Biochemistry, 39(9), 1033-1046.
10. Kurkov, S. V., & Loftsson, T. (2013). Cyclodextrins. International Journal of Pharmaceutics, 453(1), 167-180.
Lipoic Acid-Cyclodextrin-Complex

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Additional Information

Weight 0.15 oz
Dimensions 2 × 0.5 × 0.5 in
5/5 - (2 votes)

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