Lambda Free Light Chain

Description

Lambda Free Light Chain
Catalog number: B2012210
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 1 mg
Molecular Weight or Concentration: 23 kDa
Supplied as: Solution
Applications: molecular tool for various biochemical applications
Storage: -20°C
Keywords: Bence Jones Protein-Lambda, FLC-Lambda, LFLC
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Singh G. Serum and Urine Protein Electrophoresis and Serum-Free Light Chain Assays in the Diagnosis and Monitoring of Monoclonal Gammopathies J Appl Lab Med. 2020 Nov 1;5(6):1358-1371.
2: Dispenzieri A, Kyle R, Merlini G, Miguel JS, Ludwig H, Hajek R, Palumbo A, Jagannath S, Blade J, Lonial S, Dimopoulos M, Comenzo R, Einsele H, Barlogie B, Anderson K, Gertz M, Harousseau JL, Attal M, Tosi P, Sonneveld P, Boccadoro M, Morgan G, Richardson P, Sezer O, Mateos MV, Cavo M, Joshua D, Turesson I, Chen W, Shimizu K, Powles R, Rajkumar SV, Durie BG; International Myeloma Working Group. International Myeloma Working Group guidelines for serum-free light chain analysis in multiple myeloma and related disorders Leukemia. 2009 Feb;23(2):215-24.
3: Rindlisbacher B, Schild C, Egger F, Bacher VU, Pabst T, Leichtle A, Andres M, Sédille-Mostafaie N. Serum Free Light Chain Assay: Shift Toward a Higher κ/λ Ratio J Appl Lab Med. 2020 Jan 1;5(1):114-125.
4: Ryšavá R. AL amyloidosis: advances in diagnostics and treatment Nephrol Dial Transplant. 2019 Sep 1;34(9):1460-1466.
5: Lee WS, Singh G. Serum Free Light Chain Assay in Monoclonal Gammopathic Manifestations Lab Med. 2019 Oct 10;50(4):381-389.
6: Singh G. Concentrations of Serum Free Light Chains in Kappa and Lambda Lesions in Light-Chain Myelomas Lab Med. 2019 Apr 8;50(2):189-193.
7: Volovik Y, Nimri-Ammouri S, Adler T, Barak M, Henig C. Is this a true lambda free light chain? Clin Chem Lab Med. 2022 Nov 9.
8: Bourguignon C, Chenine L, Bargnoux AS, Leray-Moragues H, Canaud B, Cristol JP, Morena M. Hemodiafiltration improves free light chain removal and normalizes κ/λ ratio in hemodialysis patients J Nephrol. 2016 Apr;29(2):251-257.
9: Farnsworth CW, Logsdon NM, Hayes JE, Rais R, Willrich MA, Gronowski AM. Limitations of Free Light Chain Assays caused by the Matrix Effect J Appl Lab Med. 2020 Mar 1;5(2):311-319.
10: Singh G. Serum Free Light Chain Assay and κ/λ Ratio Performance in Patients Without Monoclonal Gammopathies:  High False-Positive Rate Am J Clin Pathol. 2016 Aug;146(2):207-14.

Products Related to Lambda Free Light Chain can be found at Proteins