Kinase Quenching Buffer Solution


Catalog Number: B2010078 (1 mL)
Kinase quenching Buffer is a very stable and efficient kinase reaction quencher. Simply spike (1/20)th of your kinase reaction volume with the provided Kinase Quencing Buffer and mix (i.e. if reaction volume is 100 uL, add 5 uL of Kinase Quenching Buffer). Custom bulk orders are available upon request.

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SKU: B2010078 Category: Tag:


Kinase Quenching Buffer

Catalog number: B2010078
Lot number: Batch Dependent
Expiration date: Batch Dependent
Volume/Weight 1 mL
pH 8
Supplied as Ready-to-use solution
Appearance clear solution
Applications Stopping kinase reactions
Shelf-Life 1 year from date of manufacture
Storage: Keep at room temperature
Keywords: kinase quench buffer, kinase stop buffer, kinase quencher, kinase stopper
Grade Biotechnology grade. All components are highly pure (minimum 99%). All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered on a 0.22 um.
References Related to Kinase Quenching Buffer 1: Bhattacharya S, McElhanon KE, Gushchina LV, Weisleder N. Role of
phosphatidylinositol-4,5-bisphosphate 3-kinase signaling in vesicular
trafficking. Life Sci. 2016 Dec 15;167:39-45.2: Fang C, Xiao Z. Receptor-based 3D-QSAR in Drug Design: Methods and
Applications in Kinase Studies. Curr Top Med Chem. 2016;16(13):1463-77.3: Colomer J, Means AR. Physiological roles of the Ca2+/CaM-dependent protein
kinase cascade in health and disease. Subcell Biochem. 2007;45:169-214.

4: Fabbro D, Cowan-Jacob SW, Möbitz H, Martiny-Baron G. Targeting cancer with
small-molecular-weight kinase inhibitors. Methods Mol Biol. 2012;795:1-34.

5: Vieth M, Higgs RE, Robertson DH, Shapiro M, Gragg EA, Hemmerle H. Kinomics-
structural biology and chemogenomics of kinase inhibitors and targets. Biochim
Biophys Acta. 2004 Mar 11;1697(1-2):243-57.
6: Qian X, Mitchell J, Wei SJ, Williams J, Petrovich RM, Shears SB. The
Ins(1,3,4)P3 5/6-kinase/Ins(3,4,5,6)P4 1-kinase is not a protein kinase. Biochem
J. 2005 Jul 15;389(Pt 2):389-95.

7: Wang SQ, Goh SS, Chai CLL, Chen A. An efficient synthesis of an exo-enone
analogue of LL-Z1640-2 and evaluation of its protein kinase inhibitory
activities. Org Biomol Chem. 2016 Jan 14;14(2):639-645.
8: Lahiry P, Torkamani A, Schork NJ, Hegele RA. Kinase mutations in human
disease: interpreting genotype-phenotype relationships. Nat Rev Genet. 2010
9: Graziani A, Ling LE, Endemann G, Carpenter CL, Cantley LC. Purification and
characterization of human erythrocyte phosphatidylinositol 4-kinase.
Phosphatidylinositol 4-kinase and phosphatidylinositol 3-monophosphate 4-kinase
are distinct enzymes. Biochem J. 1992 May 15;284 ( Pt 1)(Pt 1):39-45.

10: Suga J, Yoshimasa Y, Yamada K, Yamamoto Y, Inoue G, Okamoto M, Hayashi T,
Shigemoto M, Kosaki A, Kuzuya H, Nakao K. Differential activation of mitogen-
activated protein kinase by insulin and epidermal growth factor in 3T3-L1
adipocytes: a possible involvement of PI3-kinase in the activation of the MAP
kinase by insulin. Diabetes. 1997 May;46(5):735-41.

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Additional information

Weight 48 oz
Dimensions 8 × 8 × 8 in

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