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Keratinocyte Growth Factor 1/FGF-7 (Human)

$695.00 $495.00

Catalog Number: B2010315 (10 ug)
Keratinocyte Growth Factor 1/FGF-7 (Human) is a high quality research product used as highly pure Keratinocyte Growth Factor 1/FGF-7 (Human) expressed in CHO. This protein acts as a mitogen peptide from the fibroblast growth factors family. This factor binds only to a splice variant of FGFR2 (FGFR2 IIIb) and is a highly specific paracrine growth factor for epithelial cells. Custom bulk orders of this product are available upon request.

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SKU: B2010315 Categories: , ,

Description

Keratinocyte Growth Factor 1/FGF-7 (Human)
Catalog number: B2010315
Lot number: Batch Dependent
Expiration Date: Batch dependent
Volume/Weight: 10 ug
pH: 7.4 upon reconstitution
Supplied as: Lyophilized Powder
Appearance: Powder
Applications: highly pure Keratinocyte Growth Factor 1/FGF-7 (Human) expressed in CHO. This protein acts as a mitogen peptide from the fibroblast growth factors family. This factor binds only to a splice variant of FGFR2 (FGFR2 IIIb) and is a highly specific paracrine growth factor for epithelial cells.
Storage: -20C
Keywords: rHuKGF-1/FGF-7; Keratinocyte Growth Factor; Fibroblast Growth Factor-7; HBGF-7
Grade: Biotechnology grade. All components are highly pure (minimum 95%). All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Nguyen D, Sulaiman OAR. Transforming Growth Factor Beta 1 Regulates
Fibroblast Growth Factor 7 Expression in Schwann Cells. Ochsner J. 2019
Spring;19(1):7-12.

2: Lee CY, Yang CY, Lin CC, Yu MC, Sheu SJ, Kuan YH. Hair growth is promoted by
BeauTop via expression of EGF and FGF‑7. Mol Med Rep. 2018 Jun;17(6):8047-8052.

3: Tsuboi R, Sato C, Kurita Y, Ron D, Rubin JS, Ogawa H. Keratinocyte growth
factor (FGF-7) stimulates migration and plasminogen activator activity of normal
human keratinocytes. J Invest Dermatol. 1993 Jul;101(1):49-53.

4: Trowbridge JM, Rudisill JA, Ron D, Gallo RL. Dermatan sulfate binds and
potentiates activity of keratinocyte growth factor (FGF-7). J Biol Chem. 2002
Nov 8;277(45):42815-20.

5: Lyakhovich A, Aksenov N, Pennanen P, Miettinen S, Ahonen MH, Syvälä H,
Ylikomi T, Tuohimaa P. Vitamin D induced up-regulation of keratinocyte growth
factor (FGF-7/KGF) in MCF-7 human breast cancer cells. Biochem Biophys Res
Commun. 2000 Jul 5;273(2):675-80.

6: Zhang T, Guan H, Yang K. Keratinocyte growth factor promotes preadipocyte
proliferation via an autocrine mechanism. J Cell Biochem. 2010 Mar
1;109(4):737-46.

7: Kovacs D, Falchi M, Cardinali G, Raffa S, Carducci M, Cota C, Amantea A,
Torrisi MR, Picardo M. Immunohistochemical analysis of keratinocyte growth
factor and fibroblast growth factor 10 expression in psoriasis. Exp Dermatol.
2005 Feb;14(2):130-7.

8: Mason IJ, Fuller-Pace F, Smith R, Dickson C. FGF-7 (keratinocyte growth
factor) expression during mouse development suggests roles in myogenesis,
forebrain regionalisation and epithelial-mesenchymal interactions. Mech Dev.
1994 Jan;45(1):15-30.

9: Strain AJ, McGuinness G, Rubin JS, Aaronson SA. Keratinocyte growth factor
and fibroblast growth factor action on DNA synthesis in rat and human
hepatocytes: modulation by heparin. Exp Cell Res. 1994 Feb;210(2):253-9.
10: Wollenhaupt K, Welter H, Brüssow KP, Einspanier R. Regulation of endometrial
fibroblast growth factor 7 (FGF-7) and its receptor FGFR2IIIb in gilts after sex
steroid replacements, and during the estrous cycle and early gestation. J Reprod
Dev. 2005 Aug;51(4):509-19.

Products Related to Keratinocyte Growth Factor 1/FGF-7 (Human) : Proteins

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