Kappa Free Light Chain from Human Urine

Description

Kappa Free Light Chain from Human Urine
Catalog number: B2012127
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 1 mg
Molecular Weight or Concentration: 23 kDa
Supplied as: Liquid
Applications: molecular tool for various biochemical applications
Storage: -20 °C
Keywords: Bence Jones Protein-Kappa, FLC-Kappa, KLC, KFLC
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Singh G. Serum and Urine Protein Electrophoresis and Serum-Free Light Chain Assays in the Diagnosis and Monitoring of Monoclonal Gammopathies J Appl Lab Med. 2020 Nov 1;5(6):1358-1371.
2: Rosenstein I, Rasch S, Axelsson M, Novakova L, Blennow K, Zetterberg H, Lycke J. Kappa free light chain index as a diagnostic biomarker in multiple sclerosis: A real-world investigation J Neurochem. 2021 Nov;159(3):618-628.
3: Ryšavá R. AL amyloidosis: advances in diagnostics and treatment Nephrol Dial Transplant. 2019 Sep 1;34(9):1460-1466.
4: Singh G. Concentrations of Serum Free Light Chains in Kappa and Lambda Lesions in Light-Chain Myelomas Lab Med. 2019 Apr 8;50(2):189-193.
5: Lee WS, Singh G. Serum Free Light Chain Assay in Monoclonal Gammopathic Manifestations Lab Med. 2019 Oct 10;50(4):381-389.
6: Hutchinson AT, Jones DR, Raison RL. Preclinical and clinical development of an anti-kappa free light chain mAb for multiple myeloma Mol Immunol. 2015 Oct;67(2 Pt A):89-94.
7: Jiang XN, Chen JF, Wang Y. [Value of Serum Free Light Chain Kappa/Lambda Ratio Detection Combined with Immunofixation Electrophoresis in the Prognosis Evaluation of Patients with Multiple Myeloma] Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2020 Feb;28(1):191-195.
8: Singh G. Serum Free Light Chain Assay and κ/λ Ratio: Performance in Patients With Monoclonal Gammopathy-High False Negative Rate for κ/λ Ratio J Clin Med Res. 2017 Jan;9(1):46-57.
9: Singh G. Serum Free Light Chain Assay and κ/λ Ratio Performance in Patients Without Monoclonal Gammopathies:  High False-Positive Rate Am J Clin Pathol. 2016 Aug;146(2):207-14.
10: Harris RA, Miller M, Donaghy D, Ashton L, Langston C, Shockey T, Moore AR. Light chain myeloma and detection of free light chains in serum and urine of dogs and cats J Vet Intern Med. 2021 Mar;35(2):1031-1040.

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