Intrinsic Factor Alkaline Phosphatase Conjugate


Catalog Number: B2010604 (0.1 mg)
Intrinsic Factor Alkaline Phosphatase Conjugate is a highly pure intrinsic factor from porcine gastric mucosa conjugated to Alkaline Phosphatase. This product has been used as versatile molecular tool in the study of the metabolism of vita,in B12 as well as the development of vitamin B12 assays. It has also been used in a wide array of other biochemical and immunological applications. Custom bulk amounts of this product are available upon request.

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SKU: B2010604 Categories: ,


Intrinsic Factor Alkaline Phosphatase Conjugate
Catalog number: B2010604
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 0.1 mg
Molecular Weight or Concentration: 0.2 mg/mL
Supplied as: Solution
Applications: versatile molecular tool in the study of the metabolism of vita,in B12 as well as the development of vitamin B12 assays
Storage: -20C
Keywords: gastric intrinsic factor (vitamin B synthesis); gastric intrinsic factor; intrinsic factor; GIF; IF; INF; IFMH; TCN3, IF-AP, IP-ALP, IF-Alakaline Phosphatase
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

1: Festen HP. Intrinsic factor secretion and cobalamin absorption. Physiology
and pathophysiology in the gastrointestinal tract. Scand J Gastroenterol Suppl.

2: Alpers DH, Russell-Jones G. Gastric intrinsic factor: the gastric and small
intestinal stages of cobalamin absorption. a personal journey. Biochimie. 2013

3: Nicolas JP, Guéant JL. Gastric intrinsic factor and its receptor. Baillieres
Clin Haematol. 1995 Sep;8(3):515-31.

Nutr Rev. 1965 Feb;23:33-5.

5: Rödbro P. Human gastric intrinsic factor secretion. Scand J Gastroenterol.

6: Kapadia CR, Serfilippi D, Voloshin K, Donaldson RM Jr. Intrinsic factor-
mediated absorption of cobalamin by guinea pig ileal cells. J Clin Invest. 1983

7: Marcoullis G, Rothenberg SP. Intrinsic factor-mediated intestinal absorption
of cobalamin in the dog. Am J Physiol. 1981 Oct;241(4):G294-9.

8: Irvine WJ. Immunoassay of gastric intrinsic factor and the titration of
antibody to intrinsic factor. Clin Exp Immunol. 1966 Jan;1(1):99-118.

9: Jacob E, Glass GB. Localization of intrinsic factor and complement fixing
intrinsic factor–intrinsic factor antibody complex in parietal cell of man.
Clin Exp Immunol. 1971 Apr;8(4):517-27.
10: Tang LH, Chokshi H, Hu CB, Gordon MM, Alpers DH. The intrinsic factor
(IF)-cobalamin receptor binding site is located in the amino-terminal portion of
IF. J Biol Chem. 1992 Nov 15;267(32):22982-6.

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