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Interferon-beta (Human, Recombinant)

$695.00 $495.00

Catalog Number: B2010306 (10 ug)
Interferon-beta (Human, Recombinant) is a high quality research product used as highly pure Interferon-beta (Human, Recombinant) expressed in HEK293. This protein acts as a cytokine with known immunomodulatory properties. This protein has been used to study COVID-19 whereby it was found to decrease viral load and improve lung condition in a marmoset model. Custom bulk orders of this product are available upon request.

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SKU: B2010306 Categories: , ,

Description

Interferon-beta (Human, Recombinant)
Catalog number: B2010306
Lot number: Batch Dependent
Expiration Date: Batch dependent
Volume/Weight: 10 ug
pH: 7.4 upon reconstitution
Supplied as: Lyophilized Powder
Appearance: Powder
Applications: highly pure Interferon-beta (Human, Recombinant) expressed in HEK293. This protein acts as a cytokine with known immunomodulatory properties. This protein has been used to study COVID-19 whereby it was found to decrease viral load and improve lung condition in a marmoset model.
Storage: -20C
Keywords: rHuIFN-β; IFNB
Grade: Biotechnology grade. All components are highly pure (minimum 95%). All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Haji Abdolvahab M, Mofrad MR, Schellekens H. Interferon Beta: From Molecular
Level to Therapeutic Effects. Int Rev Cell Mol Biol. 2016;326:343-72.

2: Markowitz CE. Interferon-beta: mechanism of action and dosing issues.
Neurology. 2007 Jun 12;68(24 Suppl 4):S8-11.

3: Wanve M, Kaur H, Sarmah D, Saraf J, Pravalika K, Vats K, Kalia K, Borah A,
Yavagal DR, Dave KR, Bhattacharya P. Therapeutic spectrum of interferon-β in
ischemic stroke. J Neurosci Res. 2019 Feb;97(2):116-127.

4: Jacobs LD, Cookfair DL, Rudick RA, Herndon RM, Richert JR, Salazar AM,
Fischer JS, Goodkin DE, Granger CV, Simon JH, Alam JJ, Bartoszak DM, Bourdette
DN, Braiman J, Brownscheidle CM, Coats ME, Cohan SL, Dougherty DS, Kinkel RP,
Mass MK, Munschauer FE 3rd, Priore RL, Pullicino PM, Scherokman BJ, Whitham RH,
et al. Intramuscular interferon beta-1a for disease progression in relapsing
multiple sclerosis. The Multiple Sclerosis Collaborative Research Group (MSCRG).
Ann Neurol. 1996 Mar;39(3):285-94.

5: Zhou X, Tang G. Intravenous Interferon β-1a for Severe ARDS. JAMA. 2020 Aug
4;324(5):515.

6: Placebo-controlled multicentre randomised trial of interferon beta-1b in
treatment of secondary progressive multiple sclerosis. European Study Group on
interferon beta-1b in secondary progressive MS. Lancet. 1998 Nov
7;352(9139):1491-7.

7: Randomised double-blind placebo-controlled study of interferon beta-1a in
relapsing/remitting multiple sclerosis. PRISMS (Prevention of Relapses and
Disability by Interferon beta-1a Subcutaneously in Multiple Sclerosis) Study
Group. Lancet. 1998 Nov 7;352(9139):1498-504.
8: McCormack PL, Scott LJ. Interferon-beta-1b: a review of its use in relapsing-
remitting and secondary progressive multiple sclerosis. CNS Drugs.
2004;18(8):521-46.

Products Related to Interferon-beta (Human, Recombinant) : Proteins

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