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Insulin-like Growth Factor-1 (Human)

$595.00 $395.00

Catalog Number: B2010278 (10 ug)
Insulin-like Growth Factor-1 (Human) is a high quality research product used as highly pure Insulin-like Growth Factor-1 (Human) expressed in E. coli. This protein acts as a mitogenic cytokine that binds to IGF type 1 receptor. This protein modulates cell growth in many tissues, such as nervous tissue, lymphoid tissue, reproductive tissue, smooth muscle and more. Custom bulk orders of this product are available upon request.

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SKU: B2010278 Categories: , ,

Description

Insulin-like Growth Factor-1 (Human)
Catalog number: B2010278
Lot number: Batch Dependent
Expiration Date: Batch dependent
Volume/Weight: 10 ug
pH: 7.4 upon reconstitution
Supplied as: Lyophilized Powder
Appearance: Powder
Applications: highly pure Insulin-like Growth Factor-1 (Human) expressed in E. coli. This protein acts as a mitogenic cytokine that binds to IGF type 1 receptor. This protein modulates cell growth in many tissues, such as nervous tissue, lymphoid tissue, reproductive tissue, smooth muscle and more.
Storage: -20C
Keywords: rHuIGF-1; IGF-IA; Somatamedin C; MGF; IGF-I
Grade: Biotechnology grade. All components are highly pure (minimum 95%). All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Nicholls AR, Holt RI. Growth Hormone and Insulin-Like Growth Factor-1. Front
Horm Res. 2016;47:101-14.

2: Rothe MJ, Altman RD, Falanga V. Plasma somatomedin-C levels in systemic
sclerosis. Br J Dermatol. 1988 Nov;119(5):639-42.

3: Saito Y, Ishii Y, Niwa M, Ueda I. Direct expression of a synthetic
somatomedin C gene in Escherichia coli by use of a two-cistron system. J
Biochem. 1987 May;101(5):1281-8.

4: Chatelain P, Perrard-Sapori MH, Jaillard C, Naville D, Ruitton A, Saez J.
Somatomedin-C/insulin-like growth factor 1: a differentiating factor of
testicular function. Int J Rad Appl Instrum B. 1987;14(6):617-22.

5: Trippel SB, Corvol MT, Dumontier MF, Rappaport R, Hung HH, Mankin HJ. Effect
of somatomedin-C/insulin-like growth factor I and growth hormone on cultured
growth plate and articular chondrocytes. Pediatr Res. 1989 Jan;25(1):76-82.

6: Bennett RM, Clark SR, Campbell SM, Burckhardt CS. Low levels of somatomedin C
in patients with the fibromyalgia syndrome. A possible link between sleep and
muscle pain. Arthritis Rheum. 1992 Oct;35(10):1113-6.

7: Nishijima M. Somatomedin-C as a fetal growth promoting factor and amino acid
composition of cord blood in Japanese neonates. J Perinat Med. 1986;14(3):163-9.

8: Nickoloff BJ, Misra P, Morhenn VB, Hintz RL, Rosenfeld RG. Further
characterization of the keratinocyte somatomedin-C/insulin-like growth factor I
(SM-C/IGF-I) receptor and the biological responsiveness of cultured
keratinocytes to SM-C/IGF-I. Dermatologica. 1988;177(5):265-73.
9: Hansson HA, Engström AM, Holm S, Rosenqvist AL. Somatomedin C
immunoreactivity in the Achilles tendon varies in a dynamic manner with the
mechanical load. Acta Physiol Scand. 1988 Oct;134(2):199-208.

Products Related to Insulin-like Growth Factor-1 (Human) : Proteins

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