Human Recombinant Pleckstrin Protein


Catalog Number: B2012627 (100 ug)
Human Recombinant Pleckstrin Protein is a high quality human Pleckstrin protein with His tag and expressed in E. coli. This product has been used as molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request.

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SKU: B2012627 Categories: , Tag:


Human Recombinant Pleckstrin Protein
Catalog number: B2012627
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 100 ug
Molecular Weight or Concentration: 41.9 kDa
Supplied as: Lyophilized Powder
Applications: molecular tool for various biochemical applications
Storage: -20°C
Keywords: Pleckstrin Protein, Human, Recombinant (His Tag)
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

1: Yang XL, Zhang YL, Lai ZS, Xing FY, Liu YH. Pleckstrin homology domain of G protein-coupled receptor kinase-2 binds to PKC and affects the activity of PKC kinase World J Gastroenterol. 2003 Apr;9(4):800-3.
2: Espejo A, Côté J, Bednarek A, Richard S, Bedford MT. A protein-domain microarray identifies novel protein-protein interactions Biochem J. 2002 Nov 1;367(Pt 3):697-702.
3: Wang DS, Miller R, Shaw R, Shaw G. The pleckstrin homology domain of human beta I sigma II spectrin is targeted to the plasma membrane in vivo Biochem Biophys Res Commun. 1996 Aug 14;225(2):420-6.
4: Rodriguez MM, Ron D, Touhara K, Chen CH, Mochly-Rosen D. RACK1, a protein kinase C anchoring protein, coordinates the binding of activated protein kinase C and select pleckstrin homology domains in vitro Biochemistry. 1999 Oct 19;38(42):13787-94.
5: Touhara K, Inglese J, Pitcher JA, Shaw G, Lefkowitz RJ. Binding of G protein beta gamma-subunits to pleckstrin homology domains J Biol Chem. 1994 Apr 8;269(14):10217-20.
6: Perisic L, Lal M, Hulkko J, Hultenby K, Önfelt B, Sun Y, Dunér F, Patrakka J, Betsholtz C, Uhlen M, Brismar H, Tryggvason K, Wernerson A, Pikkarainen T. Plekhh2, a novel podocyte protein downregulated in human focal segmental glomerulosclerosis, is involved in matrix adhesion and actin dynamics Kidney Int. 2012 Nov;82(10):1071-83.
7: Lee SY, Mansour M, Pohajdak B. B2-1, a Sec7- and pleckstrin homology domain-containing protein, localizes to the Golgi complex Exp Cell Res. 2000 May 1;256(2):515-21.
8: Li P, Xu Y, Li X, Bartlam M. Crystallization and preliminary X-ray crystallographic analysis of the human CKIP-1 pleckstrin homology domain Acta Crystallogr Sect F Struct Biol Cryst Commun. 2013 Mar 1;69(Pt 3):324-7.
9: Kimber WA, Trinkle-Mulcahy L, Cheung PC, Deak M, Marsden LJ, Kieloch A, Watt S, Javier RT, Gray A, Downes CP, Lucocq JM, Alessi DR. Evidence that the tandem-pleckstrin-homology-domain-containing protein TAPP1 interacts with Ptd(3,4)P2 and the multi-PDZ-domain-containing protein MUPP1 in vivo Biochem J. 2002 Feb 1;361(Pt 3):525-36.
10: Civera C, Simon B, Stier G, Sattler M, Macias MJ. Structure and dynamics of the human pleckstrin DEP domain: distinct molecular features of a novel DEP domain subfamily Proteins. 2005 Feb 1;58(2):354-66.

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