Human Pepsinogen II

Product Description

Human Pepsinogen II
Catalog number: B2012233
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 100 ug
Molecular Weight or Concentration: 1,000 U/mg
Supplied as: Lyophilized
Applications: molecular tool for various biochemical applications
Storage: -20°C
Keywords: Pepsinogen C, PG II, PGC, Gastricsin, Pepsinogen 2
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Di Mario F, Crafa P, Barchi A, Franzoni L, Franceschi M, Russo M, Bricca L, Brozzi L, Rodriguez Castro K, Rugge M. Pepsinogen II in gastritis and Helicobacter pylori infection Helicobacter. 2022 Apr;27(2):e12872.
2: Mansour-Ghanaei F, Joukar F, Baghaee M, Sepehrimanesh M, Hojati A. Only serum pepsinogen I and pepsinogen I/II ratio are specific and sensitive biomarkers for screening of gastric cancer Biomol Concepts. 2019 May 31;10(1):82-90.
3: Cai Q, Zhu C, Yuan Y, Feng Q, Feng Y, Hao Y, Li J, Zhang K, Ye G, Ye L, Lv N, Zhang S, Liu C, Li M, Liu Q, Li R, Pan J, Yang X, Zhu X, Li Y, Lao B, Ling A, Chen H, Li X, Xu P, Zhou J, Liu B, Du Z, Du Y, Li Z; Gastrointestinal Early Cancer Prevention & Treatment Alliance of China (GECA). Development and validation of a prediction rule for estimating gastric cancer risk in the Chinese high-risk population: a nationwide multicentre study Gut. 2019 Sep;68(9):1576-1587.
4: Miki K. [Pepsinogen I and II] Nihon Rinsho. 1999 Dec;57 Suppl:567-9.
5: Tanaka M, Fukui M, Kuroda M, Yamazaki M, Hasegawa G, Oda Y, Naito Y, Toda H, Yoshikawa T, Nakamura N. Pepsinogen I/II ratio is related to glucose, triacylglycerol, and uric acid levels Nutrition. 2012 Apr;28(4):418-21.
6: Begum A, Baten MA, Begum Z, Ahsan MM, Rahman SF, Chowdhury F, Khan AH. Role of Serum Pepsinogen I and II Ratio in Screening of Gastric Carcinoma Mymensingh Med J. 2017 Jul;26(3):628-634.
7: Massarrat S, Haj-Sheykholeslami A. Increased Serum Pepsinogen II Level as a Marker of Pangastritis and Corpus-Predominant Gastritis in Gastric Cancer Prevention Arch Iran Med. 2016 Feb;19(2):137-40.
8: Simadibrata M. Pepsinogen I and II and the ratio pepsinogen I/II in detecting atrophic gastritis Acta Med Indones. 2009 Jul;41(3):105-6.
9: Becker T, Rapp W. Characterization of human pepsin II obtained from purified gastric pepsinogen II Klin Wochenschr. 1979 Jul 15;57(14):719-24.
10: Yu H, Liu Y, Jiang S, Zhou Y, Guan Z, Dong S, Chu FF, Kang C, Gao Q. Serum pepsinogen II levels are doubled with Helicobacter pylori infection in an asymptomatic population of 40,383 Chinese subjects Medicine (Baltimore). 2021 Jul 9;100(27):e26562.

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