Human Low Density Lipoproteins

Product Description

Human Low Density Lipoproteins
Catalog number: B2027103
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 5 mg
Molecular Weight or Concentration: NA
Supplied as: Solution
Storage: 2-8°C
Keywords: Low Density Lipoprotein, LDL, human protein, lipid research, cellular uptake, receptor-mediated endocytosis, apolipoprotein B-100, plasma-derived, cell culture, cell proliferation

References:
1. Goldstein JL, Ho YK, Basu SK, Brown MS. Binding site on macrophages that mediates uptake and degradation of acetylated low density lipoprotein, producing massive cholesterol deposition. Proc Natl Acad Sci U S A. 1979;76(1):333-337.
2. Pitas RE, Boyles J, Mahley RW, Bissell DM. Uptake of chemically modified low density lipoproteins in vivo is mediated by specific endothelial cells. J Cell Biol. 1985;100(1):103-117.
3. Kume N, Arai H, Kawai C, Kita T. Receptors for modified low-density lipoproteins on human endothelial cells: different mechanisms for uptake of acetylated and oxidized low-density lipoproteins. J Clin Invest. 1991;88(3):995-1002.
4. Tintut Y, Patel J, Parhami F, Demer LL. Acetylated low-density lipoprotein stimulates human vascular smooth muscle cell calcification by promoting osteoblastic differentiation and inhibiting phagocytosis. Circulation. 2002;106(21):2711-2717.
5. Brown MS, Goldstein JL. Lipoprotein metabolism in the macrophage: implications for cholesterol deposition in atherosclerosis. Annu Rev Biochem. 1983;52:223-261.
6. Krieger M, Herz J. Structures and functions of scavenger receptors. Annu Rev Biochem. 1994;63:601-637.
7. Via DP, Dresel HA, Cheng SL, Gotto AM. Murine macrophage scavenger receptor: in vivo expression and regulation as determined by anti-scavenger receptor monoclonal antibodies. J Biol Chem. 1985;260(12):7379-7386.
8. Nagayama M, Arai H, Kita T, Oho S. Differences in the metabolism of oxidatively modified low density lipoprotein and acetylated low density lipoprotein by human endothelial cells. Biochem Biophys Res Commun. 1994;202(1):405-411.
9. Sparrow CP, Parthasarathy S, Steinberg D. A macrophage receptor that recognizes oxidized low density lipoprotein but not acetylated low density lipoprotein. J Biol Chem. 1989;264(5):2599-2604.
10. Lougheed M, Moore ED, Gase JC. Uptake and degradation of acetylated low density lipoprotein by human vascular endothelial cells via high-affinity binding. Arterioscler Thromb Vasc Biol. 1997;17(4):721-729.
Human Low Density Lipoproteins

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