Interleukin-1 alpha (IL-1A, Human Recombinant)


Catalog Number: B2010264 (10 ug)
Human Interleukin-1 alpha (IL-1A) is a high quality research product used as highly pure recombinant human Interleukin 1 alpha (expressed in E. coli). IL-1 alpha a non-glycosylated 159 amino residues protein with a MW of 18 kDa. Custom bulk orders of this product are available upon request.

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SKU: B2010264 Categories: ,


Interleukin-1 alpha (IL-1A, Human Recombinant)
Catalog number: B2010264
Lot number: Batch Dependent
Expiration Date: Batch dependent
Volume/Weight: 10 ug
pH: n/a
Supplied as: Reconstitute before use
Appearance: Solid
Applications: highly pure recombinant human Interleukin 1 alpha (expressed in E. coli). IL-1 alpha a non-glycosylated 159 amino residues protein with a MW of 18 kDa.
Storage: -20C
Keywords: rHuIL-1α; Hematopoietin-1; IL1A; IL1F1; IL-1 alpha
Grade: Biotechnology grade. All components are highly pure (minimum 95%). All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through0.22 um.

1: Bou-Dargham MJ, Khamis ZI, Cognetta AB, Sang QA. The Role of Interleukin-1 in
Inflammatory and Malignant Human Skin Diseases and the Rationale for Targeting
Interleukin-1 Alpha. Med Res Rev. 2017 Jan;37(1):180-216.

2: Malik A, Kanneganti TD. Function and regulation of IL-1α in inflammatory
diseases and cancer. Immunol Rev. 2018 Jan;281(1):124-137.

3: Di Paolo NC, Shayakhmetov DM. Interleukin 1α and the inflammatory process.
Nat Immunol. 2016 Jul 19;17(8):906-13.

4: Ghasemi M, Kashani E, Fayyaz A, Attar M, Shahbazi M. Interleukin-1 alpha
variation is associated with the risk of developing preeclampsia. Eur J Obstet
Gynecol Reprod Biol. 2015 Oct;193:75-8.

5: Espinosa-Cotton M, Rodman Iii SN, Ross KA, Jensen IJ, Sangodeyi-Miller K,
McLaren AJ, Dahl RA, Gibson-Corley KN, Koch AT, Fu YX, Badovinac VP, Laux D,
Narasimhan B, Simons AL. Interleukin-1 alpha increases anti-tumor efficacy of
cetuximab in head and neck squamous cell carcinoma. J Immunother Cancer. 2019
Mar 19;7(1):79.

6: de Mooij CEM, Netea MG, van der Velden WJFM, Blijlevens NMA. Targeting the
interleukin-1 pathway in patients with hematological disorders. Blood. 2017 Jun

7: Schultz K, Murthy V, Tatro JB, Beasley D. Endogenous interleukin-1 alpha
promotes a proliferative and proinflammatory phenotype in human vascular smooth
muscle cells. Am J Physiol Heart Circ Physiol. 2007 Jun;292(6):H2927-34.

8: Mendoza-Carrera F, Ramírez-López G, Hernández-Ramos LE, Leal-Cortés C,
Portilla-de-Buen E, Castro-Martínez XH, Castro Martínez AG, López-Quintero A,
Flores-Martínez SE, Sánchez-Corona J. Interleukin-1 Alpha Polymorphisms Are
Associated With Body Mass Index in Male But Not in Female Adolescents. Arch Med
Res. 2019 Apr;50(3):151-157.

9: Albuquerque C, Morinha F, Magalhães J, Requicha J, Dias I, Guedes-Pinto H,
Bastos E, Viegas C. Variants in the interleukin-1 alpha and beta genes, and the
risk for periodontal disease in dogs. J Genet. 2015 Dec;94(4):651-9.

10: Marchiori LLM, Doi MY, Marchiori GM, de Souza GV, Poli-Frederico RC,
Ciquinato DSA. Interleukin-1 alpha gene polymorphism (IL-1α) and susceptibility
to tinnitus in the elderly. Noise Health. 2019 Mar-Apr;21(99):77-82.

11: Goh YC, Chan SW, Siar CH. Parenchyma-stromal interleukin-1 alpha and
interleukin-6 overexpressions in ameloblastoma correlate with the aggressive
phenotype. Malays J Pathol. 2019 Dec;41(3):303-311.

12: Badie A, Saliminejad K, Salahshourifar I, Khorram Khorshid HR. Interleukin 1
alpha (IL1A) polymorphisms and risk of endometriosis in Iranian
population: a case-control study. Gynecol Endocrinol. 2020 Feb;36(2):135-138.

13: Nakayama Y, Ishikawa C, Tamaki K, Senba M, Fujita J, Mori N. Interleukin-1
alpha produced by human T-cell leukaemia virus type I-infected T cells induces
intercellular adhesion molecule-1 expression on lung epithelial cells. J Med
Microbiol. 2011 Dec;60(Pt 12):1750-1761.
14: de Jongh CM, Khrenova L, Kezic S, Rustemeyer T, Verberk MM, John SM.
Polymorphisms in the interleukin-1 gene influence the stratum corneum
interleukin-1 alpha concentration in uninvolved skin of patients with chronic
irritant contact dermatitis. Contact Dermatitis. 2008 May;58(5):263-8.

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