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Human Gamma Thrombin

$795.00

Catalog Number: B2013733 (1 mg)
Human Gamma Thrombin is a high quality non-clotting derivative of thrombin. This product has been used as molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request.

Live enquiry about this product via Text/SMS: 1-858-900-3210.

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SKU: B2013733 Categories: , Tag:

Description

Human Gamma Thrombin
Catalog number: B2013733
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 1 mg
Molecular Weight or Concentration: 12 kDa
Supplied as: Powder
Applications: molecular tool for various biochemical applications
Storage: -20°C
Keywords: Human Gamma Thrombin
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Davie EW, Kulman JD. An overview of the structure and function of thrombin Semin Thromb Hemost. 2006 Apr;32 Suppl 1:3-15.
2: Jandrot-Perrus M, Guillin MC, Nurden AT. Human gamma-thrombin: lack of correlation between a platelet functional response and glycoprotein V hydrolysis Thromb Haemost. 1987 Oct 28;58(3):915-20.
3: Naldini A, Morena E, Filippi I, Pucci A, Bucci M, Cirino G, Carraro F. Thrombin inhibits IFN-gamma production in human peripheral blood mononuclear cells by promoting a Th2 profile J Interferon Cytokine Res. 2006 Nov;26(11):793-9.
4: Brower MS, Walz DA, Garry KE, Fenton JW 2nd. Human neutrophil elastase alters human alpha_thrombin function: limited proteolysis near the gamma-cleavage site results in decreased fibrinogen clotting and platelet-stimulatory activity Blood. 1987 Mar;69(3):813-9.
5: Bezeaud A, Denninger MH, Guillin MC. Interaction of human alpha_thrombin and gamma_thrombin with antithrombin III, protein C and thrombomodulin Eur J Biochem. 1985 Dec 16;153(3):491-6.
6: Rydel TJ, Yin M, Padmanabhan KP, Blankenship DT, Cardin AD, Correa PE, Fenton JW 2nd, Tulinsky A. Crystallographic structure of human gamma_thrombin J Biol Chem. 1994 Sep 2;269(35):22000-6.
7: Soslau G, Prest PJ, Class R, Jost M, Mathews L. Inhibition of gamma_thrombin-induced human platelet aggregation by histone H1subtypes and H1.3 fragments Platelets. 2009 Aug;20(5):349-56.
8: Witting JI, Miller TM, Fenton JW 2nd. Human alpha- and gamma_thrombin specificity with tripeptide p-nitroanalide substrates under physiologically relevant conditions Thromb Res. 1987 May 15;46(4):567-74.
9: Bishop PD, Lewis KB, Schultz J, Walker KM. Comparison of recombinant human_ thrombin_ and plasma-derived human alpha_thrombin Semin Thromb Hemost. 2006 Apr;32 Suppl 1:86-97.
10: Huntington JA. Thrombin plasticity Biochim Biophys Acta. 2012 Jan;1824(1):246-52.

Products Related to Human Gamma Thrombin can be found at Enzymes

Additional information

Weight 48 oz
Dimensions 8 × 8 × 8 in

How to Order

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4- Order by phone: 1-858-900-3210 (6 am – 8 pm PST).

5- Order by Text/SMS: 1-858-900-3210 (6 am – 8 pm PST).