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Fibroblast Growth Factor-6 (Human)

$695.00 $495.00

Catalog Number: B2010360 (10 ug)
Human Fibroblast Growth Factor-6 is a high quality research product used as highly pure Human Fibroblast Growth Factor-6 expressed in E. coli. This protein acts as a potent mitogen for fibroblasts, vascular endothelial cells, and prostate carcinoma cells. Custom bulk orders of this product are available upon request.

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SKU: B2010360 Categories: , ,

Description

Human Fibroblast Growth Factor-6
Catalog number: B2010360
Lot number: Batch Dependent
Expiration Date: Batch dependent
Volume/Weight: 10 ug
pH: 7.4 upon reconstitution
Supplied as: Lyophilized Powder
Appearance: Powder
Applications: highly pure Human Fibroblast Growth Factor-6 expressed in E. coli. This protein acts as a potent mitogen for fibroblasts, vascular endothelial cells, and prostate carcinoma cells.
Storage: -20C
Keywords: rHuFGF-6; HBGF-6; HST-2; HSTF-2
Grade: Biotechnology grade. All components are highly pure (minimum 95%). All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Othman A, Mubarak R, Sabry D. Fibroblast growth factor-6 enhances CDK2
and MATK expression in microvesicles derived from human stem cells
extracted from exfoliated deciduous teeth. F1000Res. 2018 May 22;7:622.

2: Shamsi F, Xue R, Huang TL, Lundh M, Liu Y, Leiria LO, Lynes MD, Kempf E, Wang
CH, Sugimoto S, Nigro P, Landgraf K, Schulz T, Li Y, Emanuelli B, Kothakota S,
Williams LT, Jessen N, Pedersen SB, Böttcher Y, Blüher M, Körner A, Goodyear LJ,
Mohammadi M, Kahn CR, Tseng YH. FGF6 and FGF9 regulate UCP1 expression
independent of brown adipogenesis. Nat Commun. 2020 Mar 17;11(1):1421.

3: Xu Y, Tan Q, Hu P, Yao J. Characterization and expression analysis of FGF6
(fibroblast growth factor 6) genes of grass carp (Ctenopharyngodon idellus)
reveal their regulation on muscle growth. Fish Physiol Biochem. 2019
Oct;45(5):1649-1662.

4: Coulier F, Pizette S, Ollendorff V, deLapeyrière O, Birnbaum D. The human and
mouse fibroblast growth factor 6 (FGF6) genes and their products: possible
implication in muscle development. Prog Growth Factor Res. 1994;5(1):1-14.

5: Rescan PY. Identification of a fibroblast growth factor 6 (FGF6) gene in a
non-mammalian vertebrate: continuous expression of FGF6 accompanies muscle fiber
hyperplasia. Biochim Biophys Acta. 1998 Dec 22;1443(3):305-14.

6: Ropiquet F, Giri D, Kwabi-Addo B, Mansukhani A, Ittmann M. Increased
expression of fibroblast growth factor 6 in human prostatic intraepithelial
neoplasia and prostate cancer. Cancer Res. 2000 Aug 1;60(15):4245-50. PMID:
10945637.

7: Batoz M, Coll Fresno PM, Pizette S, Raffioni S, Birnbaum D, Coulier F. A
diphtheria toxin/fibroblast growth factor 6 mitotoxin selectively kills
fibroblast growth factor receptor-expressing cell lines. Cell Growth Differ.
1995 Sep;6(9):1143-9. PMID: 8519691.

8: Xu Z, Ramachandran S, Gunasekaran M, Zhou F, Trulock E, Kreisel D, Hachem R,
Mohanakumar T. MicroRNA-144 dysregulates the transforming growth factor-β
signaling cascade and contributes to the development of bronchiolitis obliterans
syndrome after human lung transplantation. J Heart Lung Transplant. 2015
Sep;34(9):1154-62.

9: Pessina A, Gagliardi G, Croera C, Foti P, Dassi C, Brambilla P, Neri MG.
Secretion of basic fibroblast growth factor (FGF-2) by WEHI-3B myelomonocytic
leukemia cells. Growth Factors. 2002 Sep;20(3):121-9.
10: Armand AS, Laziz I, Chanoine C. FGF6 in myogenesis. Biochim Biophys Acta.
2006 Aug;1763(8):773-8.

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