Human Factor XIIa beta

Description

Human Factor XIIa beta
Catalog number: B2014064
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 0.1 mg
Molecular Weight or Concentration: 30 kDa
Supplied as: N/A
Applications: molecular tool for various biochemical applications
Storage: -20°C
Keywords: Human Factor XIIa beta
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Dementiev A, Silva A, Yee C, Li Z, Flavin MT, Sham H, Partridge JR. Structures of human plasma _-factor XIIa cocrystallized with potent inhibitors Blood Adv. 2018 Mar 13;2(5):549-558.
2: Fujikawa K, McMullen BA. Amino acid sequence of human beta-factor_XIIa J Biol Chem. 1983 Sep 25;258(18):10924-33.
3: Liu W, de Veer SJ, Huang YH, Sengoku T, Okada C, Ogata K, Zdenek CN, Fry BG, Swedberg JE, Passioura T, Craik DJ, Suga H. An Ultrapotent and Selective Cyclic Peptide Inhibitor of Human _-Factor XIIa in a Cyclotide Scaffold J Am Chem Soc. 2021 Nov 10;143(44):18481-18489.
4: Hojima Y, Pierce JV, Pisano JJ. Pumpkin seed inhibitor of human factor_XIIa (activated Hageman factor) and bovine trypsin Biochemistry. 1982 Aug 3;21(16):3741-6.
5: Esnouf MP, Burgess AI, Dodds AW, Sarphie AF, Miller GJ. A monoclonal antibody raised against human beta-factor_XIIa which also recognizes alpha-factor XIIa but not factor XII or complexes of factor XIIa with C1 esterase inhibitor Thromb Haemost. 2000 Jun;83(6):874-81.
6: Wynn R, Laskowski M Jr. Inhibition of human_beta-factor_XIIa by squash family serine proteinase inhibitors Biochem Biophys Res Commun. 1990 Feb 14;166(3):1406-10.
7: Tankersley DL, Alving BM, Finlayson JS. Preparation of beta-XIIa (Hageman factor fragment) from human plasma Thromb Res. 1982 Feb 15;25(4):307-17.
8: Papageorgiou PC, Simos D, Boomsma F, Rojkjaer R, Osmond DH. Angiotensin converting enzyme-regulated, noncholinergic sympathoadrenal catecholamine release mediates the cardiovascular actions of human ‘new pressor protein’ related to coagulation beta-factor XIIa Can J Cardiol. 2009 Apr;25(4):e100-8.
9: McMullen BA, Fujikawa K. Amino acid sequence of the heavy chain of human alpha-factor_XIIa (activated Hageman factor) J Biol Chem. 1985 May 10;260(9):5328-41.
10: Cool DE, Edgell CJ, Louie GV, Zoller MJ, Brayer GD, MacGillivray RT. Characterization of human blood coagulation factor XII cDNA. Prediction of the primary structure of factor XII and the tertiary structure of beta-factor XIIa J Biol Chem. 1985 Nov 5;260(25):13666-76.

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