Human Factor XI

Product Description

Human Factor XI
Catalog number: B2013448
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 0.1 mg
Molecular Weight or Concentration: 160 kDa
Supplied as: Solution
Applications: molecular tool for various biochemical applications
Storage: -20°C
Keywords: Plasma Thromboplastin Antecedent
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Cao Y, Wang Y, Zhou Z, Pan C, Jiang L, Zhou Z, Meng Y, Charugundla S, Li T, Allayee H, Seldin MM, Lusis AJ. Liver-heart cross-talk mediated by coagulation factor XI protects against heart failure Science. 2022 Sep 23;377(6613):1399-1406.
2: Fredenburgh JC, Weitz JI. Factor XI as a Target for New Anticoagulants Hamostaseologie. 2021 Apr;41(2):104-110.
3: De Caterina R, Prisco D, Eikelboom JW. Factor XI inhibitors: cardiovascular perspectives Eur Heart J. 2023 Jan 21;44(4):280-292.
4: Bolton-Maggs PH. Factor XI deficiency Baillieres Clin Haematol. 1996 Jun;9(2):355-68.
5: Gomez K, Bolton-Maggs P. Factor XI deficiency Haemophilia. 2008 Nov;14(6):1183-9.
6: Wheeler AP, Gailani D. Why factor XI deficiency is a clinical concern Expert Rev Hematol. 2016 Jul;9(7):629-37.
7: Mohammed BM, Matafonov A, Ivanov I, Sun MF, Cheng Q, Dickeson SK, Li C, Sun D, Verhamme IM, Emsley J, Gailani D. An update on factor XI structure and function Thromb Res. 2018 Jan;161:94-105.
8: Gailani D, Sun MF, Sun Y. A comparison of murine and human factor XI Blood. 1997 Aug 1;90(3):1055-64.
9: Huynh K. Liver-derived factor XI protects against HFpEF Nat Rev Cardiol. 2022 Dec;19(12):781.
10: Sun MF, Baglia FA, Ho D, Martincic D, Ware RE, Walsh PN, Gailani D. Defective binding of factor XI-N248 to activated human platelets Blood. 2001 Jul 1;98(1):125-9.

Products Related to Human Factor XI can be found at Proteins