Human ErbB2 Protein

Description

Human ErbB2 Protein
Catalog number: B2012390
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 20 ug
Molecular Weight or Concentration: 43.4 kDa
Supplied as: Solution
Applications: molecular tool for various biochemical applications
Storage: -20°C
Keywords: NEU, NGL, HER2, TKR1, HER-2, c-erb B2, HER-2/neu, Receptor tyrosine-protein kinase erbB-2
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Moasser MM. The oncogene HER2: its signaling and transforming functions and its role in human cancer pathogenesis Oncogene. 2007 Oct 4;26(45):6469-87.
2: Mery B, Toussaint P, Heudel PE, Dufresne A, Carbonnaux M, Vanacker H, Bachelot T, Trédan O. Nouvelles stratégies thérapeutiques dans les cancers du sein HER2-surexprimé: New therapeutic strategies in HER2-positive breast cancer Bull Cancer. 2021 Dec;108(11S):11S8-11S18.
3: Rüschoff J, Nagelmeier I, Jasani B, Stoss O. ISH-based HER2 diagnostics Pathologe. 2021 Nov;42(Suppl 1):62-68.
4: Valabrega G, Montemurro F, Aglietta M. Trastuzumab: mechanism of action, resistance and future perspectives in HER2-overexpressing breast cancer Ann Oncol. 2007 Jun;18(6):977-84.
5: Li BT, Ross DS, Aisner DL, Chaft JE, Hsu M, Kako SL, Kris MG, Varella-Garcia M, Arcila ME. HER2 Amplification and HER2 Mutation Are Distinct Molecular Targets in Lung Cancers J Thorac Oncol. 2016 Mar;11(3):414-9.
6: Wang DS, Liu ZX, Lu YX, Bao H, Wu X, Zeng ZL, Liu Z, Zhao Q, He CY, Lu JH, Wang ZQ, Qiu MZ, Wang F, Wang FH, Li YH, Wang XN, Xie D, Jia WH, Shao YW, Xu RH. Liquid biopsies to track trastuzumab resistance in metastatic HER2-positive gastric cancer Gut. 2019 Jul;68(7):1152-1161.
7: Garberis I, Andre F, Lacroix-Triki M. L’intelligence artificielle pourrait-elle intervenir dans l’aide au diagnostic des cancers du sein ? – L’exemple de HER2: Could artificial intelligence play a role in breast cancer diagnosis? – The example of HER2 Bull Cancer. 2021 Dec;108(11S):11S35-11S45.
8: Vion R, Fontanilles M, Di Fiore F, Clatot F. Place des biopsies liquides dans le diagnostic et la caractérisation moléculaire des cancers du sein: Role of liquid biopsies in the diagnosis and molecular characterization of breast cancer Bull Cancer. 2021 Dec;108(11S):11S46-11S54.
9: Deluche É, Vincent-Salomon A. « HER2-faible », un nouveau concept dans la prise en charge des cancers du sein: HER2-low breast cancer: a new concept in breast cancer treatment strategy Bull Cancer. 2021 Dec;108(11S):11S1-11S7.
10: Kuesters S, Maurer M, Burger AM, Metz T, Fiebig HH. Correlation of ErbB2 gene status, mRNA and protein expression in a panel of >100 human tumor xenografts of different origin Onkologie. 2006 Jun;29(6):249-56.

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