Human Casein Kinase 2 Holoenzyme


Catalog Number: B2012376 (10 ug )
Human Casein Kinase 2 Holoenzyme is a high quality Human Casein Kinase 2 Holoenzyme expressed in E. coli. This product has been used as molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request.

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Human Casein Kinase 2 Holoenzyme
Catalog number: B2012376
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 10 ug
Molecular Weight or Concentration: 140 kDa
Supplied as: Solution
Applications: molecular tool for various biochemical applications
Storage: -20°C
Keywords: CK2H
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

1: Rodríguez F, Allende CC, Allende JE. Protein kinase casein kinase 2 holoenzyme produced ectopically in human cells can be exported to the external side of the cellular membrane Proc Natl Acad Sci U S A. 2005 Mar 29;102(13):4718-23.
2: Engel M, Issinger OG, Lascu I, Seib T, Dooley S, Zang KD, Welter C. Phosphorylation of nm23/nucleoside diphosphate kinase by casein kinase 2 in vitro Biochem Biophys Res Commun. 1994 Mar 15;199(2):1041-8.
3: Bodenbach L, Fauss J, Robitzki A, Krehan A, Lorenz P, Lozeman FJ, Pyerin W. Recombinant human casein kinase II. A study with the complete set of subunits (alpha, alpha’ and beta), site-directed autophosphorylation mutants and a bicistronically expressed holoenzyme Eur J Biochem. 1994 Feb 15;220(1):263-73.
4: Blanquet PR. Casein kinase 2 as a potentially important enzyme in the nervous system Prog Neurobiol. 2000 Feb;60(3):211-46.
5: Li C, Liu X, Lin X, Chen X. Structure-activity relationship of 7 flavonoids on recombinant human protein kinase CK2 holoenzyme Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2009 Jan;34(1):20-6.
6: Golden D, Cantley LG. Casein kinase 2 prevents mesenchymal transformation by maintaining Foxc2 in the cytoplasm Oncogene. 2015 Sep 3;34(36):4702-12.
7: Boldyreff B, James P, Staudenmann W, Issinger OG. Ser2 is the autophosphorylation site in the beta subunit from bicistronically expressed human casein kinase-2 and from native rat liver casein kinase-2 beta Eur J Biochem. 1993 Dec 1;218(2):515-21.
8: Lozeman FJ, Litchfield DW, Piening C, Takio K, Walsh KA, Krebs EG. Isolation and characterization of human cDNA clones encoding the alpha and the alpha’ subunits of casein kinase II Biochemistry. 1990 Sep 11;29(36):8436-47.
9: Li CM, Liu XG, Lin XC, Chen XW, Liang NC. [Effects of mitoxantrone on the activity of human protein kinase CK2 holoenzyme] Ai Zheng. 2008 Aug;27(8):809-15.
10: Lolli G, Naressi D, Sarno S, Battistutta R. Characterization of the oligomeric states of the CK2 α(2)β(2) holoenzyme in solution Biochem J. 2017 Jul 6;474(14):2405-2416.

Products Related to Human Casein Kinase 2 Holoenzyme can be found at Enzymes

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