Human BHMT2 Protein


Catalog Number: B2011598 (50 µg)
Human BHMT2 Protein is a high quality recombinant human BHMT2 protein His tagged and expressed in E. coli. This product has been used as molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request.

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Human BHMT2 Protein
Catalog number: B2011598
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 50 µg
Molecular Weight or Concentration: 500 µg/mL
Supplied as: Solution
Applications: molecular tool for various biochemical applications
Storage: -20 °C
Keywords: BHMT2 protein (His tag), S-methylmethionine-homocysteine S-methyltransferase BHMT2 isoform 1 protein, betaine–homocysteine S-methyltransferase 2 protein
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

1: Li F, Feng Q, Lee C, Wang S, Pelleymounter LL, Moon I, Eckloff BW, Wieben ED, Schaid DJ, Yee V, Weinshilboum RM. Human betaine-homocysteine methyltransferase (BHMT) and BHMT2: common gene sequence variation and functional characterization Mol Genet Metab. 2008 Jul;94(3):326-35.
2: Feng Q, Kalari K, Fridley BL, Jenkins G, Ji Y, Abo R, Hebbring S, Zhang J, Nye MD, Leeder JS, Weinshilboum RM. Betaine-homocysteine methyltransferase: human liver genotype-phenotype correlation Mol Genet Metab. 2011 Feb;102(2):126-33.
3: Ganu RS, Ishida Y, Koutmos M, Kolokotronis SO, Roca AL, Garrow TA, Schook LB. Evolutionary Analyses and Natural Selection of Betaine-Homocysteine S-Methyltransferase (BHMT) and BHMT2 Genes PLoS One. 2015 Jul 27;10(7):e0134084.
4: Chadwick LH, McCandless SE, Silverman GL, Schwartz S, Westaway D, Nadeau JH. Betaine-homocysteine methyltransferase-2: cDNA cloning, gene sequence, physical mapping, and expression of the human and mouse genes Genomics. 2000 Nov 15;70(1):66-73.
5: Dufresne J, Bowden P, Thavarajah T, Florentinus-Mefailoski A, Chen ZZ, Tucholska M, Norzin T, Ho MT, Phan M, Mohamed N, Ravandi A, Stanton E, Slutsky AS, Dos Santos CC, Romaschin A, Marshall JC, Addison C, Malone S, Heyland D, Scheltens P, Killestein J, Teunissen C, Diamandis EP, Siu KWM, Marshall JG. The plasma peptides of breast versus ovarian cancer Clin Proteomics. 2019 Dec 23;16:43.
6: Vossen CY, Koeleman BP, Hasstedt SJ, Nijman IJ, Renkens IJ, Callas PW, Rosendaal FR, Bovill EG. Genetic variants associated with protein C levels J Thromb Haemost. 2013 Apr;11(4):715-23.
7: Mostowska A, Hozyasz KK, Biedziak B, Misiak J, Jagodzinski PP. Polymorphisms located in the region containing BHMT and BHMT2 genes as maternal protective factors for orofacial clefts Eur J Oral Sci. 2010 Aug;118(4):325-32.
8: Pellanda H, Namour F, Fofou-Caillierez M, Bressenot A, Alberto JM, Chéry C, Ayav A, Bronowicki JP, Guéant JL, Forges T. A splicing variant leads to complete loss of function of betaine-homocysteine methyltransferase (BHMT) gene in hepatocellular carcinoma Int J Biochem Cell Biol. 2012 Feb;44(2):385-92.
9: Zhu H, Curry S, Wen S, Wicker NJ, Shaw GM, Lammer EJ, Yang W, Jafarov T, Finnell RH. Are the betaine-homocysteine methyltransferase (BHMT and BHMT2) genes risk factors for spina bifida and orofacial clefts? Am J Med Genet A. 2005 Jun 15;135(3):274-7.
10: Wang P, Wu T, Schwender H, Wang H, Shi B, Wang ZQ, Yuan Y, Liu DJ, Wang MY, Li J, Zhou ZB, Zhu HP, Beaty TH. Evidence of interaction between genes in the folate/homocysteine metabolic pathway in controlling risk of non-syndromic oral cleft Oral Dis. 2018 Jul;24(5):820-828.

Products Related to Human BHMT2 Protein can be found at Proteins

Additional information

Weight 48 oz
Dimensions 8 × 8 × 8 in

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