Human ARF4 Protein


Catalog Number: B2011757 (100 µg)
Human ARF4 Protein is a high quality recombinant human ARF4 protein His tagged and expressed in E.coli. This product has been used as molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request.

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SKU: B2011757 Categories: , Tag:


Human ARF4 Protein
Catalog number: B2011757
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 100 µg
Molecular Weight or Concentration: 0.5 mg/mL
Supplied as: Solution
Applications: molecular tool for various biochemical applications
Storage: -20 °C
Keywords: ARF-4, ARF 4 protein, ARF 4, ARF-4 protein, ADP-ribosylation factor 4 protein, ARF2, ARF4
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

1: Pearring JN, San Agustin JT, Lobanova ES, Gabriel CJ, Lieu EC, Monis WJ, Stuck MW, Strittmatter L, Jaber SM, Arshavsky VY, Pazour GJ. Loss of Arf4 causes severe degeneration of the exocrine pancreas but not cystic kidney disease or retinal degeneration PLoS Genet. 2017 Apr 14;13(4):e1006740.
2: Deitz SB, Wu C, Silve S, Howell KE, Melançon P, Kahn RA, Franzusoff A. Human ARF4 expression rescues sec7 mutant yeast cells Mol Cell Biol. 1996 Jul;16(7):3275-84.
3: Follit JA, San Agustin JT, Jonassen JA, Huang T, Rivera-Perez JA, Tremblay KD, Pazour GJ. Arf4 is required for Mammalian development but dispensable for ciliary assembly PLoS Genet. 2014 Feb 20;10(2):e1004170.
4: Dejgaard SY, Presley JF. Class II Arfs require a brefeldin-A-sensitive factor for Golgi association Biochem Biophys Res Commun. 2020 Sep 10;530(1):301-306.
5: Neufeldt CJ, Cortese M, Scaturro P, Cerikan B, Wideman JG, Tabata K, Moraes T, Oleksiuk O, Pichlmair A, Bartenschlager R. ER-shaping atlastin proteins act as central hubs to promote flavivirus replication and virion assembly Nat Microbiol. 2019 Dec;4(12):2416-2429.
6: Reiling JH, Olive AJ, Sanyal S, Carette JE, Brummelkamp TR, Ploegh HL, Starnbach MN, Sabatini DM. A CREB3-ARF4 signalling pathway mediates the response to Golgi stress and susceptibility to pathogens Nat Cell Biol. 2013 Dec;15(12):1473-85.
7: Wang J, Fresquez T, Kandachar V, Deretic D. The Arf GEF GBF1 and Arf4 synergize with the sensory receptor cargo, rhodopsin, to regulate ciliary membrane trafficking J Cell Sci. 2017 Dec 1;130(23):3975-3987.
8: Zhang Q, Wu L, Bai B, Li D, Xiao P, Li Q, Zhang Z, Wang H, Li L, Jiang Q. Quantitative Proteomics Reveals Association of Neuron Projection Development Genes ARF4, KIF5B, and RAB8A With Hirschsprung Disease Mol Cell Proteomics. 2021;20:100007.
9: Zhang N, Ke Y, Zhang L. Interplay between hepatitis C virus and ARF4 Virol Sin. 2017 Dec;32(6):533-536.
10: Mazelova J, Astuto-Gribble L, Inoue H, Tam BM, Schonteich E, Prekeris R, Moritz OL, Randazzo PA, Deretic D. Ciliary targeting motif VxPx directs assembly of a trafficking module through Arf4 EMBO J. 2009 Feb 4;28(3):183-92.

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