Human ApoBEC4 Protein


Catalog Number: B2011748 (100 µg)
Human ApoBEC4 Protein is a high quality recombinant human ApoBEC4 protein His tagged and expressed in E.coli. This product has been used as molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request.

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SKU: B2011748 Categories: ,


Human ApoBEC4 Protein
Catalog number: B2011748
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 100 µg
Molecular Weight or Concentration: 1 mg/mL
Supplied as: Solution
Applications: molecular tool for various biochemical applications
Storage: -20 °C
Keywords: C1orf169 protein, ApoBEC 4 protein, ApoBEC-4 protein, Apolipoprotein B mRNA Editing Enzyme Catalytic Polypeptide-Like 4
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

1: Shi M, Tan L, Zhang Y, Meng C, Wang W, Sun Y, Song C, Liu W, Liao Y, Yu S, Ren T, Ding Z, Liu X, Qiu X, Ding C. Characterization and functional analysis of chicken APOBEC4 Dev Comp Immunol. 2020 May;106:103631.
2: Marino D, Perković M, Hain A, Jaguva Vasudevan AA, Hofmann H, Hanschmann KM, Mühlebach MD, Schumann GG, König R, Cichutek K, Häussinger D, Münk C. APOBEC4 Enhances the Replication of HIV-1 PLoS One. 2016 Jun 1;11(6):e0155422.
3: Lada AG, Krick CF, Kozmin SG, Mayorov VI, Karpova TS, Rogozin IB, Pavlov YI. Mutator effects and mutation signatures of editing deaminases produced in bacteria and yeast Biochemistry (Mosc). 2011 Jan;76(1):131-46.
4: Meshcheryakova A, Pietschmann P, Zimmermann P, Rogozin IB, Mechtcheriakova D. AID and APOBECs as Multifaceted Intrinsic Virus-Restricting Factors: Emerging Concepts in the Light of COVID-19 Front Immunol. 2021 Jul 1;12:690416.
5: Knisbacher BA, Gerber D, Levanon EY. DNA Editing by APOBECs: A Genomic Preserver and Transformer Trends Genet. 2016 Jan;32(1):16-28.
6: Rogozin IB, Basu MK, Jordan IK, Pavlov YI, Koonin EV. APOBEC4, a new member of the AID/APOBEC family of polynucleotide (deoxy)cytidine deaminases predicted by computational analysis Cell Cycle. 2005 Sep;4(9):1281-5.
7: Liu R, Wu P, Ogrodzki P, Mahmoud S, Liang K, Liu P, Francis SS, Khalak H, Liu D, Li J, Ma T, Chen F, Liu W, Huang X, He W, Yuan Z, Qiao N, Meng X, Alqarni B, Quilez J, Kusuma V, Lin L, Jin X, Yang C, Anton X, Koshy A, Yang H, Xu X, Wang J, Xiao P, Al Kaabi N, Fasihuddin MS, Selvaraj FA, Weber S, Al Hosani FI, Liu S, Zaher WA. Genomic epidemiology of SARS-CoV-2 in the UAE reveals novel virus mutation, patterns of co-infection and tissue specific host immune response Sci Rep. 2021 Jul 7;11(1):13971.
8: Krishnan A, Iyer LM, Holland SJ, Boehm T, Aravind L. Diversification of AID/APOBEC-like deaminases in metazoa: multiplicity of clades and widespread roles in immunity Proc Natl Acad Sci U S A. 2018 Apr 3;115(14):E3201-E3210.
9: Santa-Marta M, Aires da Silva F, Fonseca AM, Rato S, Goncalves J. HIV-1 Vif protein blocks the cytidine deaminase activity of B-cell specific AID in E. coli by a similar mechanism of action Mol Immunol. 2007 Jan;44(4):583-90.
10: Zhu M, Wang Y, Wang C, Shen W, Liu J, Geng L, Cheng Y, Dai J, Jin G, Ma H, Hu Z, Shen H. The eQTL-missense polymorphisms of APOBEC3H are associated with lung cancer risk in a Han Chinese population Sci Rep. 2015 Oct 13;5:14969.

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