Human Adenylate Kinase Isoenzyme 1 (AK 1)

Product Description

Human Adenylate Kinase Isoenzyme 1 (AK 1)
Catalog number: B2015564
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 10 ug
Molecular Weight or Concentration: 23.7 kDa (214 aa)
Supplied as: Solution
Applications: a molecular tool for various biochemical applications
Storage: -20°C
Keywords: ATP-AMP Transphosphorylase 1, ATP:AMP Phosphotransferase, Adenylate Monophosphate Kinase, Myokinase
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Wujak M, Kozakiewicz A, Ciarkowska A, Loch JI, Barwiolek M, Sokolowska Z, Budny M, Wojtczak A. Assessing the Interactions of Statins with Human Adenylate Kinase Isoenzyme 1: Fluorescence and Enzyme Kinetic Studies Int J Mol Sci. 2021 May 24;22(11):5541.
2: Murthy VV. Adenylate kinase mimics creatine kinase-MM isoenzyme in a CK isoenzyme electrophoresis assay J Clin Lab Anal. 1994;8(3):140-3.
3: Klepinin A, Ounpuu L, Guzun R, Chekulayev V, Timohhina N, Tepp K, Shevchuk I, Schlattner U, Kaambre T. Simple oxygraphic analysis for the presence of adenylate kinase 1 and 2 in normal and tumor cells J Bioenerg Biomembr. 2016 Oct;48(5):531-548.
4: Fujisawa K. Regulation of Adenine Nucleotide Metabolism by Adenylate Kinase Isozymes: Physiological Roles and Diseases Int J Mol Sci. 2023 Mar 14;24(6):5561.
5: Von Zabern I, Wittmann-Liebold B, Untucht-Grau R, Schirmer RH, Pai EF. Primary and tertiary structure of the principal human adenylate kinase Eur J Biochem. 1976 Sep;68(1):281-90.
6: Lee Y, Kim JW, Lee SM, Kim HJ, Lee KS, Park C, Choe IS. Cloning and expression of human adenylate kinase 2 isozymes: differential expression of adenylate kinase 1 and 2 in human muscle tissues J Biochem. 1998 Jan;123(1):47-54.
7: Bruns GA, Regina VM. Adenylate kinase 2, a mitochondrial enzyme Biochem Genet. 1977 Jun;15(5-6):477-86.
8: Fujisawa K, Wakazaki M, Matsuzaki A, Matsumoto T, Yamamoto N, Noma T, Takami T. Adenylate Kinase Isozyme 3 Regulates Mitochondrial Energy Metabolism and Knockout Alters HeLa Cell Metabolism Int J Mol Sci. 2022 Apr 13;23(8):4316.
9: Bruns GA, Gerald PS. Expression of the human adenylate kinase isozymes, phosphopyruvate hydratase, 6-phosphogluconate dehydrogenase, and phosphoglucomutase-1 in man-rodent somatic cell hybrids Biochem Genet. 1976 Feb;14(1-2):1-17.
10: Liu H, Pu Y, Amina Q, Wang Q, Zhang M, Song J, Guo J, Mardan M. Prognostic and therapeutic potential of Adenylate kinase 2 in lung adenocarcinoma Sci Rep. 2019 Nov 28;9(1):17757.

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