Human ACE2 Conjugated to Phosphatase Alkaline

Product Description

Human ACE2 Conjugated to Phosphatase Alkaline
Catalog number: B2010704
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 50 ug
Molecular Weight or Concentration: na
Supplied as: Solution
Applications: versatile molecular tool in the research and development of assays involving the human recptor ACE2
Storage: -20C
Keywords: ACE2 Alkaline Phosphatase, Alkaline Phosphatase conjugated to ACE2. ACE2-AP conjugate, ACE2 [AP], ACE2 ALP-Conjugated
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Senapati S, Banerjee P, Bhagavatula S, Kushwaha PP, Kumar S. Contributions of human ACE2 and TMPRSS2 in determining host-pathogen interaction of COVID-19 J Genet. 2021;100(1):12.
2: Li MY, Li L, Zhang Y, Wang XS. Expression of the SARS-CoV-2 cell receptor gene ACE2 in a wide variety of human tissues Infect Dis Poverty. 2020 Apr 28;9(1):45.
3: Zou X, Chen K, Zou J, Han P, Hao J, Han Z. Single-cell RNA-seq data analysis on the receptor ACE2 expression reveals the potential risk of different human organs vulnerable to 2019-nCoV infection Front Med. 2020 Apr;14(2):185-192.
4: Beyerstedt S, Casaro EB, Rangel ÉB. COVID-19: angiotensin-converting enzyme 2 (ACE2) expression and tissue susceptibility to SARS-CoV-2 infection Eur J Clin Microbiol Infect Dis. 2021 May;40(5):905-919.
5: Hussain M, Jabeen N, Raza F, Shabbir S, Baig AA, Amanullah A, Aziz B. Structural variations in human ACE2 may influence its binding with SARS-CoV-2 spike protein J Med Virol. 2020 Sep;92(9):1580-1586.
6: Zhang H, Rostami MR, Leopold PL, Mezey JG, O’Beirne SL, Strulovici-Barel Y, Crystal RG. Expression of the SARS-CoV-2 ACE2 Receptor in the Human Airway Epithelium Am J Respir Crit Care Med. 2020 Jul 15;202(2):219-229.
7: Ashraf UM, Abokor AA, Edwards JM, Waigi EW, Royfman RS, Hasan SA, Smedlund KB, Hardy AMG, Chakravarti R, Koch LG. SARS-CoV-2, ACE2 expression, and systemic organ invasion Physiol Genomics. 2021 Feb 1;53(2):51-60.
8: Devaux CA, Rolain JM, Raoult D. ACE2 receptor polymorphism: Susceptibility to SARS-CoV-2, hypertension, multi-organ failure, and COVID-19 disease outcome J Microbiol Immunol Infect. 2020 Jun;53(3):425-435.
9: Chakraborty S. Evolutionary and structural analysis elucidates mutations on SARS-CoV2 spike protein with altered human ACE2 binding affinity Biochem Biophys Res Commun. 2021 Jan 1;534:374-380.
10: Mercurio I, Tragni V, Busto F, De Grassi A, Pierri CL. Protein structure analysis of the interactions between SARS-CoV-2 spike protein and the human ACE2 receptor: from conformational changes to novel neutralizing antibodies Cell Mol Life Sci. 2021 Feb;78(4):1501-1522.

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