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Folic Acid BSA Conjugate Solution

$495.00 $350.00

Catalog #: P2010026 (0.5 mg)
Concentrated solution of Bovine Serum Albumin (BSA) conjugated to Folic Acid (also known as Folate when in its anionic form). A carbon spacer arm of 10.0 Å links BSA to the Folic Acid moiety. Each BSA molecule contains several Folic Acid units. Dilutions of the provided conjugate can be made in 1X Phosphate Buffer Saline, pH 7.4.

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Description

Folic Acid BSA Conjugate

Product Data Sheet Download PDF
MSDS Download PDF
Catalog number: P2010026
Lot number: 0120P0026
Expiration date: 2024-04
Purity: > 95%
Concentration: 1 mg/mL
Package Size: 0.5 mg
Molecular Weight: 71 kDa (average)
Storage: -20°C. Avoid repeated freeze/thaw cycles.
Other names: BSA-Folic Acid, Folic Acid-BSA, BSA conjugated to Folic Acid, Folic Acid Bovine Serum Albumin Conjugate, Folic Acid [BSA], BSA-Folate, Folate-BSA, BSA conjugated to Folate, Folate Bovine Serum Albumin Conjugate, Folate [BSA]
Keywords: 5 Methyl THFA; 5 Methyltetrahydrofolate; Folate; Tetrahydrofolate; Tetrahydrofolic acid; THFA, folate-bsa
Buffer: 1X Phosphate Buffer Saline, pH 7.4.

 

About Folic Acid

Folic acid (also known as folate when present in its anionic form) is water-soluble B vitamin. Folic acid plays important physiological roles and its active form, Tetrahydrofolic Acid (THFA), is obtained by an enzymatic reaction in which folic acid is reduced into THFA by the enzyme dihydrofolate reductase. THFA is important in many biosynthetic reactions that include the transfer of single-carbon containing groups and the biosynthesis of purines, thymidine, and certain amino acids.

References

  • Maekawa A, Nakajima H, Kawata T. Folic acid. 1999 Oct;57(10):2254-60.
  • Naithani M, Saxena V, Mirza AA, Kumari R, Sharma K, Bharadwaj J. Assessment of Folic Acid Supplementation in Pregnant Women by Estimation of Serum Levels of Tetrahydrofolic Acid, Dihydrofolate Reductase, and Homocysteine. Scientifica (Cairo). 2016;2016:1520685.
  • Chen J, Chen X, Yang Z, Tan X, Wang J, Chen Y. Preparation and characterization of folic acid functionalized bioactive glass for targeted delivery and sustained release of methotrexate. J Biomed Mater Res A. 2019 Feb;107(2):319-329.
  • Ai J, Xu Y, Li D, Liu Z, Wang E. Folic acid as delivery vehicles: targeting folate conjugated fluorescent nanoparticles to tumors imaging. Talanta. 2012 Nov 15;101:32-7.
  • Morris MS. The role of B vitamins in preventing and treating cognitive impairment and decline. Adv Nutr. 2012 Nov 1;3(6):801-12.

 

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